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Page 1
A lactate-dependent shift of glycolysis mediates synaptic and cognitive processes in male mice.
Fernández-Moncada I, Lavanco G, Fundazuri UB, Bollmohr N, Mountadem S, Dalla Tor T, Hachaguer P, Julio-Kalajzic F, Gisquet D, Serrat R, Bellocchio L, Cannich A, Fortunato-Marsol B, Nasu Y, Campbell RE, Drago F, Cannizzaro C, Ferreira G, Bouzier-Sore AK, Pellerin L, Bolaños JP, Bonvento G, Barros LF, Oliet SHR, Panatier A, Marsicano G. Fernández-Moncada I, et al. Among authors: bonvento g. Nat Commun. 2024 Aug 9;15(1):6842. doi: 10.1038/s41467-024-51008-2. Nat Commun. 2024. PMID: 39122700 Free PMC article.
Development of an AAV-based model of tauopathy targeting retinal ganglion cells and the mouse visual pathway to study the role of microglia in Tau pathology.
Duwat C, Léal P, Vautheny A, Aurégan G, Joséphine C, Gaillard MC, Hérard AS, Jan C, Gipchtein P, Mitja J, Fouquet S, Niepon ML, Hantraye P, Brouillet E, Bonvento G, Cambon K, Bemelmans AP. Duwat C, et al. Among authors: bonvento g. Neurobiol Dis. 2023 Jun 1;181:106116. doi: 10.1016/j.nbd.2023.106116. Epub 2023 Apr 11. Neurobiol Dis. 2023. PMID: 37054900 Free article.
Reactive astrocytes promote proteostasis in Huntington's disease through the JAK2-STAT3 pathway.
Abjean L, Ben Haim L, Riquelme-Perez M, Gipchtein P, Derbois C, Palomares MA, Petit F, Hérard AS, Gaillard MC, Guillermier M, Gaudin-Guérif M, Aurégan G, Sagar N, Héry C, Dufour N, Robil N, Kabani M, Melki R, De la Grange P, Bemelmans AP, Bonvento G, Deleuze JF, Hantraye P, Flament J, Bonnet E, Brohard S, Olaso R, Brouillet E, Carrillo-de Sauvage MA, Escartin C. Abjean L, et al. Among authors: bonvento g. Brain. 2023 Jan 5;146(1):149-166. doi: 10.1093/brain/awac068. Brain. 2023. PMID: 35298632
The C-Terminal Domain of LRRK2 with the G2019S Substitution Increases Mutant A53T α-Synuclein Toxicity in Dopaminergic Neurons In Vivo.
Cresto N, Gardier C, Gaillard MC, Gubinelli F, Roost P, Molina D, Josephine C, Dufour N, Auregan G, Guillermier M, Bernier S, Jan C, Gipchtein P, Hantraye P, Chartier-Harlin MC, Bonvento G, Van Camp N, Taymans JM, Cambon K, Liot G, Bemelmans AP, Brouillet E. Cresto N, et al. Among authors: bonvento g. Int J Mol Sci. 2021 Jun 23;22(13):6760. doi: 10.3390/ijms22136760. Int J Mol Sci. 2021. PMID: 34201785 Free PMC article.
THY-Tau22 mouse model accumulates more tauopathy at late stage of the disease in response to microglia deactivation through TREM2 deficiency.
Vautheny A, Duwat C, Aurégan G, Joséphine C, Hérard AS, Jan C, Mitja J, Gipchtein P, Gaillard MC, Buée L, Blum D, Hantraye P, Bonvento G, Brouillet E, Cambon K, Bemelmans AP. Vautheny A, et al. Among authors: bonvento g. Neurobiol Dis. 2021 Jul;155:105398. doi: 10.1016/j.nbd.2021.105398. Epub 2021 May 18. Neurobiol Dis. 2021. PMID: 34019997 Free article.
Neuronal tau species transfer to astrocytes and induce their loss according to tau aggregation state.
Maté de Gérando A, d'Orange M, Augustin E, Joséphine C, Aurégan G, Gaudin-Guérif M, Guillermier M, Hérard AS, Stimmer L, Petit F, Gipchtein P, Jan C, Escartin C, Selingue E, Carvalho K, Blum D, Brouillet E, Hantraye P, Gaillard MC, Bonvento G, Bemelmans AP, Cambon K. Maté de Gérando A, et al. Among authors: bonvento g. Brain. 2021 May 7;144(4):1167-1182. doi: 10.1093/brain/awab011. Brain. 2021. PMID: 33842937
94 results