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Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes.
Rubio-Aliaga I, Przemeck GK, Fuchs H, Gailus-Durner V, Adler T, Hans W, Horsch M, Rathkolb B, Rozman J, Schrewe A, Wagner S, Hoelter SM, Becker L, Klopstock T, Wurst W, Wolf E, Klingenspor M, Ivandic BT, Busch DH, Beckers J, Hrabé de Angelis M. Rubio-Aliaga I, et al. PLoS One. 2009 Jun 29;4(6):e6054. doi: 10.1371/journal.pone.0006054. PLoS One. 2009. PMID: 19562077 Free PMC article.
New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis.
Sabrautzki S, Rubio-Aliaga I, Hans W, Fuchs H, Rathkolb B, Calzada-Wack J, Cohrs CM, Klaften M, Seedorf H, Eck S, Benet-Pagès A, Favor J, Esposito I, Strom TM, Wolf E, Lorenz-Depiereux B, Hrabě de Angelis M. Sabrautzki S, et al. Mamm Genome. 2012 Aug;23(7-8):416-30. doi: 10.1007/s00335-012-9397-z. Epub 2012 Apr 21. Mamm Genome. 2012. PMID: 22527485 Free PMC article.
Profiling at mRNA, protein, and metabolite levels reveals alterations in renal amino acid handling and glutathione metabolism in kidney tissue of Pept2-/- mice.
Frey IM, Rubio-Aliaga I, Siewert A, Sailer D, Drobyshev A, Beckers J, de Angelis MH, Aubert J, Bar Hen A, Fiehn O, Eichinger HM, Daniel H. Frey IM, et al. Physiol Genomics. 2007 Feb 12;28(3):301-10. doi: 10.1152/physiolgenomics.00193.2006. Epub 2006 Oct 31. Physiol Genomics. 2007. PMID: 17077276
The elevation of circulating fibroblast growth factor 23 without kidney disease does not increase cardiovascular disease risk.
Pastor-Arroyo EM, Gehring N, Krudewig C, Costantino S, Bettoni C, Knöpfel T, Sabrautzki S, Lorenz-Depiereux B, Pastor J, Strom TM, Hrabě de Angelis M, Camici GG, Paneni F, Wagner CA, Rubio-Aliaga I. Pastor-Arroyo EM, et al. Kidney Int. 2018 Jul;94(1):49-59. doi: 10.1016/j.kint.2018.02.017. Epub 2018 May 5. Kidney Int. 2018. PMID: 29735309 Free article.
Features and strategies of ENU mouse mutagenesis.
Soewarto D, Klaften M, Rubio-Aliaga I. Soewarto D, et al. Curr Pharm Biotechnol. 2009 Feb;10(2):198-213. doi: 10.2174/138920109787315079. Curr Pharm Biotechnol. 2009. PMID: 19199953 Review.
An update on renal peptide transporters.
Daniel H, Rubio-Aliaga I. Daniel H, et al. Am J Physiol Renal Physiol. 2003 May;284(5):F885-92. doi: 10.1152/ajprenal.00123.2002. Am J Physiol Renal Physiol. 2003. PMID: 12676733 Free article. Review.
67 results