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A Structural Mechanism for Noncanonical GPCR Signal Transduction in the Hedgehog Pathway.
Steiner WP, Iverson N, Venkatakrishnan V, Wu J, Stepniewski TM, Michaelson Z, Bröckel JW, Zhu JF, Bruystens J, Lee A, Nelson I, Bertinetti D, Arveseth CD, Tan G, Spaltenstein P, Xu J, Hüttenhain R, Kay M, Herberg FW, Selent J, Anand GS, Dunbrack RL Jr, Taylor SS, Myers BR. Steiner WP, et al. Among authors: myers br. bioRxiv [Preprint]. 2024 Nov 1:2024.10.31.621410. doi: 10.1101/2024.10.31.621410. bioRxiv. 2024. PMID: 39554190 Free PMC article. Preprint.
GRK2 kinases in the primary cilium initiate SMOOTHENED-PKA signaling in the Hedgehog cascade.
Walker MF, Zhang J, Steiner W, Ku PI, Zhu JF, Michaelson Z, Yen YC, Lee A, Long AB, Casey MJ, Poddar A, Nelson IB, Arveseth CD, Nagel F, Clough R, LaPotin S, Kwan KM, Schulz S, Stewart RA, Tesmer JJG, Caspary T, Subramanian R, Ge X, Myers BR. Walker MF, et al. Among authors: myers br. PLoS Biol. 2024 Aug 13;22(8):e3002685. doi: 10.1371/journal.pbio.3002685. eCollection 2024 Aug. PLoS Biol. 2024. PMID: 39138140 Free PMC article.
A simple and scalable zebrafish model of Sonic hedgehog medulloblastoma.
Casey MJ, Chan PP, Li Q, Zu JF, Jette CA, Kohler M, Myers BR, Stewart RA. Casey MJ, et al. Among authors: myers br. Cell Rep. 2024 Aug 27;43(8):114559. doi: 10.1016/j.celrep.2024.114559. Epub 2024 Jul 29. Cell Rep. 2024. PMID: 39078737 Free PMC article.
38 results