Harper JW - Search Results

1

Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor.

Huh K, Zhou X, Hayakawa H, Cho JY, Libermann TA, Jin J, Harper JW, Munger K. Huh K, et al. Among authors: harper jw. J Virol. 2007 Sep;81(18):9737-47. doi: 10.1128/JVI.00881-07. Epub 2007 Jul 3. J Virol. 2007. PMID: 17609271 Free PMC article.

2

RING finger specificity in SCF-driven protein destruction.

Jin J, Harper JW. Jin J, et al. Among authors: harper jw. Dev Cell. 2002 Jun;2(6):685-7. doi: 10.1016/s1534-5807(02)00194-6. Dev Cell. 2002. PMID: 12062077 Free article.

3

The cyclin E/Cdk2 substrate and Cajal body component p220(NPAT) activates histone transcription through a novel LisH-like domain.

Wei Y, Jin J, Harper JW. Wei Y, et al. Among authors: harper jw. Mol Cell Biol. 2003 May;23(10):3669-80. doi: 10.1128/MCB.23.10.3669-3680.2003. Mol Cell Biol. 2003. PMID: 12724424 Free PMC article.

4

A license to kill: transcriptional activation and enhanced turnover of Myc by the SCF(kp2) ubiquitin ligase.

Jin J, Harper JW. Jin J, et al. Among authors: harper jw. Cancer Cell. 2003 Jun;3(6):517-8. doi: 10.1016/s1535-6108(03)00145-4. Cancer Cell. 2003. PMID: 12842079 Free article.

5

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase.

Jin J, Shirogane T, Xu L, Nalepa G, Qin J, Elledge SJ, Harper JW. Jin J, et al. Among authors: harper jw. Genes Dev. 2003 Dec 15;17(24):3062-74. doi: 10.1101/gad.1157503. Epub 2003 Dec 17. Genes Dev. 2003. PMID: 14681206 Free PMC article.

6

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.

Welcker M, Orian A, Jin J, Grim JE, Harper JW, Eisenman RN, Clurman BE. Welcker M, et al. Among authors: harper jw. Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):9085-90. doi: 10.1073/pnas.0402770101. Epub 2004 May 18. Proc Natl Acad Sci U S A. 2004. PMID: 15150404 Free PMC article.

7

SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein.

Shirogane T, Jin J, Ang XL, Harper JW. Shirogane T, et al. Among authors: harper jw. J Biol Chem. 2005 Jul 22;280(29):26863-72. doi: 10.1074/jbc.M502862200. Epub 2005 May 24. J Biol Chem. 2005. PMID: 15917222 Free article.

8

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase.

Wei W, Jin J, Schlisio S, Harper JW, Kaelin WG Jr. Wei W, et al. Among authors: harper jw. Cancer Cell. 2005 Jul;8(1):25-33. doi: 10.1016/j.ccr.2005.06.005. Cancer Cell. 2005. PMID: 16023596 Free article.

9

Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF(Fbw7).

Sundqvist A, Bengoechea-Alonso MT, Ye X, Lukiyanchuk V, Jin J, Harper JW, Ericsson J. Sundqvist A, et al. Among authors: harper jw. Cell Metab. 2005 Jun;1(6):379-91. doi: 10.1016/j.cmet.2005.04.010. Cell Metab. 2005. PMID: 16054087 Free article.

10

Drug discovery in the ubiquitin-proteasome system.

Nalepa G, Rolfe M, Harper JW. Nalepa G, et al. Among authors: harper jw. Nat Rev Drug Discov. 2006 Jul;5(7):596-613. doi: 10.1038/nrd2056. Nat Rev Drug Discov. 2006. PMID: 16816840 Review.

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