Insulin secretory function is impaired in isolated human islets carrying the Gly(972)-->Arg IRS-1 polymorphism.
Marchetti P, Lupi R, Federici M, Marselli L, Masini M, Boggi U, Del Guerra S, Patanè G, Piro S, Anello M, Bergamini E, Purrello F, Lauro R, Mosca F, Sesti G, Del Prato S.
Marchetti P, et al.
Diabetes. 2002 May;51(5):1419-24. doi: 10.2337/diabetes.51.5.1419.
Diabetes. 2002.
PMID: 11978638