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Involvement of the snake toxin receptor CLEC-2, in podoplanin-mediated platelet activation, by cancer cells.
Suzuki-Inoue K, Kato Y, Inoue O, Kaneko MK, Mishima K, Yatomi Y, Yamazaki Y, Narimatsu H, Ozaki Y. Suzuki-Inoue K, et al. Among authors: ozaki y. J Biol Chem. 2007 Sep 7;282(36):25993-6001. doi: 10.1074/jbc.M702327200. Epub 2007 Jul 6. J Biol Chem. 2007. PMID: 17616532 Free article. Clinical Trial.
D., Schweighoffer, E., Zitzmann, N., Morita, T., Tybulewicz, V. L., Ozaki, Y., and Watson, S. P. (2006) Blood 107, 542-549). Therefore, we sought to evaluate whether CLEC-2 serves as a physiological counterpart for podoplanin. ...
D., Schweighoffer, E., Zitzmann, N., Morita, T., Tybulewicz, V. L., Ozaki, Y., and Watson, S. P. (2006) Blood 107, 542-549). T …
A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.
Suzuki-Inoue K, Fuller GL, García A, Eble JA, Pöhlmann S, Inoue O, Gartner TK, Hughan SC, Pearce AC, Laing GD, Theakston RD, Schweighoffer E, Zitzmann N, Morita T, Tybulewicz VL, Ozaki Y, Watson SP. Suzuki-Inoue K, et al. Among authors: ozaki y. Blood. 2006 Jan 15;107(2):542-9. doi: 10.1182/blood-2005-05-1994. Epub 2005 Sep 20. Blood. 2006. PMID: 16174766 Free article.
Molecular analysis of the pathophysiological binding of the platelet aggregation-inducing factor podoplanin to the C-type lectin-like receptor CLEC-2.
Kato Y, Kaneko MK, Kunita A, Ito H, Kameyama A, Ogasawara S, Matsuura N, Hasegawa Y, Suzuki-Inoue K, Inoue O, Ozaki Y, Narimatsu H. Kato Y, et al. Among authors: ozaki y. Cancer Sci. 2008 Jan;99(1):54-61. doi: 10.1111/j.1349-7006.2007.00634.x. Epub 2007 Oct 18. Cancer Sci. 2008. PMID: 17944973 Free PMC article.
Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets.
Suzuki-Inoue K, Inoue O, Ding G, Nishimura S, Hokamura K, Eto K, Kashiwagi H, Tomiyama Y, Yatomi Y, Umemura K, Shin Y, Hirashima M, Ozaki Y. Suzuki-Inoue K, et al. Among authors: ozaki y. J Biol Chem. 2010 Aug 6;285(32):24494-507. doi: 10.1074/jbc.M110.130575. Epub 2010 Jun 4. J Biol Chem. 2010. PMID: 20525685 Free PMC article.
D., Schweighoffer, E., Zitzmann, N., Morita, T., Tybulewicz, V. L., Ozaki, Y., and Watson, S. P. (2006) Blood 107, 542-549). Podoplanin, which is expressed on the surface of tumor cells, is an endogenous ligand for CLEC-2 and facilitates tumor metastasis by inducing …
D., Schweighoffer, E., Zitzmann, N., Morita, T., Tybulewicz, V. L., Ozaki, Y., and Watson, S. P. (2006) Blood 107, 542-549). P …
The novel platelet activation receptor CLEC-2.
Suzuki-Inoue K, Inoue O, Ozaki Y. Suzuki-Inoue K, et al. Among authors: ozaki y. Platelets. 2011;22(5):380-4. doi: 10.3109/09537104.2011.556274. Epub 2011 Jun 30. Platelets. 2011. PMID: 21714702 Free article. Review.
Platelet activation receptor CLEC-2 regulates blood/lymphatic vessel separation by inhibiting proliferation, migration, and tube formation of lymphatic endothelial cells.
Osada M, Inoue O, Ding G, Shirai T, Ichise H, Hirayama K, Takano K, Yatomi Y, Hirashima M, Fujii H, Suzuki-Inoue K, Ozaki Y. Osada M, et al. Among authors: ozaki y. J Biol Chem. 2012 Jun 22;287(26):22241-52. doi: 10.1074/jbc.M111.329987. Epub 2012 May 3. J Biol Chem. 2012. PMID: 22556408 Free PMC article.
2,157 results