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ApoER2 expression increases Abeta production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of gamma-secretase activity.
Fuentealba RA, Barría MI, Lee J, Cam J, Araya C, Escudero CA, Inestrosa NC, Bronfman FC, Bu G, Marzolo MP. Fuentealba RA, et al. Among authors: bronfman fc. Mol Neurodegener. 2007 Jul 9;2:14. doi: 10.1186/1750-1326-2-14. Mol Neurodegener. 2007. PMID: 17620134 Free PMC article.
Laminin inhibits amyloid-beta-peptide fibrillation.
Bronfman FC, Garrido J, Alvarez A, Morgan C, Inestrosa NC. Bronfman FC, et al. Neurosci Lett. 1996 Nov 8;218(3):201-3. doi: 10.1016/s0304-3940(96)13147-5. Neurosci Lett. 1996. PMID: 8945763
TrkA receptor activation by nerve growth factor induces shedding of the p75 neurotrophin receptor followed by endosomal gamma-secretase-mediated release of the p75 intracellular domain.
Urra S, Escudero CA, Ramos P, Lisbona F, Allende E, Covarrubias P, Parraguez JI, Zampieri N, Chao MV, Annaert W, Bronfman FC. Urra S, et al. Among authors: bronfman fc. J Biol Chem. 2007 Mar 9;282(10):7606-15. doi: 10.1074/jbc.M610458200. Epub 2007 Jan 9. J Biol Chem. 2007. PMID: 17215246 Free article.
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