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Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy.
Morrow PK, Wulf GM, Ensor J, Booser DJ, Moore JA, Flores PR, Xiong Y, Zhang S, Krop IE, Winer EP, Kindelberger DW, Coviello J, Sahin AA, Nuñez R, Hortobagyi GN, Yu D, Esteva FJ. Morrow PK, et al. Among authors: krop ie. J Clin Oncol. 2011 Aug 10;29(23):3126-32. doi: 10.1200/JCO.2010.32.2321. Epub 2011 Jul 5. J Clin Oncol. 2011. PMID: 21730275 Free PMC article. Clinical Trial.
The ethical use of mandatory research biopsies.
Olson EM, Lin NU, Krop IE, Winer EP. Olson EM, et al. Among authors: krop ie. Nat Rev Clin Oncol. 2011 Aug 2;8(10):620-5. doi: 10.1038/nrclinonc.2011.114. Nat Rev Clin Oncol. 2011. PMID: 21808265 Free PMC article. Review.
Further progress in HER2-directed therapy.
Krop I, Winer EP. Krop I, et al. Lancet Oncol. 2012 Jan;13(1):2-3. doi: 10.1016/S1470-2045(11)70388-6. Lancet Oncol. 2012. PMID: 22225715 No abstract available.
A phase II study of trastuzumab emtansine in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer who were previously treated with trastuzumab, lapatinib, an anthracycline, a taxane, and capecitabine.
Krop IE, LoRusso P, Miller KD, Modi S, Yardley D, Rodriguez G, Guardino E, Lu M, Zheng M, Girish S, Amler L, Winer EP, Rugo HS. Krop IE, et al. J Clin Oncol. 2012 Sep 10;30(26):3234-41. doi: 10.1200/JCO.2011.40.5902. Epub 2012 May 29. J Clin Oncol. 2012. PMID: 22649126 Clinical Trial.
235 results