Sai K - Search Results

1

Haplotypes and a novel defective allele of CES2 found in a Japanese population.

Kim SR, Sai K, Tanaka-Kagawa T, Jinno H, Ozawa S, Kaniwa N, Saito Y, Akasawa A, Matsumoto K, Saito H, Kamatani N, Shirao K, Yamamoto N, Yoshida T, Minami H, Ohtsu A, Saijo N, Sawada J. Kim SR, et al. Among authors: sai k. Drug Metab Dispos. 2007 Oct;35(10):1865-72. doi: 10.1124/dmd.107.015339. Epub 2007 Jul 19. Drug Metab Dispos. 2007. PMID: 17640957 Clinical Trial.

2

Expression of CYP2A6 in tumor cells augments cellular sensitivity to tegafur.

Murayama N, Sai K, Nakajima Y, Kaniwa N, Ozawa S, Ohno Y, Sawada J. Murayama N, et al. Among authors: sai k. Jpn J Cancer Res. 2001 May;92(5):524-8. doi: 10.1111/j.1349-7006.2001.tb01125.x. Jpn J Cancer Res. 2001. PMID: 11376561 Free PMC article.

3

Apparent low frequency of sequence variability within the proximal promoter region of the cytochrome P450 (CYP) 3A5 gene in established cell lines from Japanese individuals.

Nakamura T, Saito Y, Murayama N, Saeki M, Soyama A, Sai K, Ozawa S, Sawada J. Nakamura T, et al. Among authors: sai k. Biol Pharm Bull. 2001 Aug;24(8):954-7. doi: 10.1248/bpb.24.954. Biol Pharm Bull. 2001. PMID: 11510493 Free article.

4

A new metabolite of irinotecan in which formation is mediated by human hepatic cytochrome P-450 3A4.

Sai K, Kaniwa N, Ozawa S, Sawada JI. Sai K, et al. Drug Metab Dispos. 2001 Nov;29(11):1505-13. Drug Metab Dispos. 2001. PMID: 11602529

5

Non-synonymous single nucleotide alterations found in the CYP2C8 gene result in reduced in vitro paclitaxel metabolism.

Soyama A, Saito Y, Hanioka N, Murayama N, Nakajima O, Katori N, Ishida S, Sai K, Ozawa S, Sawada JI. Soyama A, et al. Among authors: sai k. Biol Pharm Bull. 2001 Dec;24(12):1427-30. doi: 10.1248/bpb.24.1427. Biol Pharm Bull. 2001. PMID: 11767116 Free article.

6

Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: an association between single nucleotide polymorphisms in the 5'-untranslated region and exon 28.

Itoda M, Saito Y, Soyama A, Saeki M, Murayama N, Ishida S, Sai K, Nagano M, Suzuki H, Sugiyama Y, Ozawa S, Sawada Ji J. Itoda M, et al. Among authors: sai k. Drug Metab Dispos. 2002 Apr;30(4):363-4. doi: 10.1124/dmd.30.4.363. Drug Metab Dispos. 2002. PMID: 11901087

7

An analytical method for irinotecan (CPT-11) and its metabolites using a high-performance liquid chromatography: parallel detection with fluorescence and mass spectrometry.

Sai K, Kaniwa N, Ozawa S, Sawada J. Sai K, et al. Biomed Chromatogr. 2002 May;16(3):209-18. doi: 10.1002/bmc.137. Biomed Chromatogr. 2002. PMID: 11920947

8

Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients.

Jinno H, Saeki M, Saito Y, Tanaka-Kagawa T, Hanioka N, Sai K, Kaniwa N, Ando M, Shirao K, Minami H, Ohtsu A, Yoshida T, Saijo N, Ozawa S, Sawada J. Jinno H, et al. Among authors: sai k. J Pharmacol Exp Ther. 2003 Aug;306(2):688-93. doi: 10.1124/jpet.103.051250. Epub 2003 May 1. J Pharmacol Exp Ther. 2003. PMID: 12730278

9

Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan.

Sai K, Kaniwa N, Itoda M, Saito Y, Hasegawa R, Komamura K, Ueno K, Kamakura S, Kitakaze M, Shirao K, Minami H, Ohtsu A, Yoshida T, Saijo N, Kitamura Y, Kamatani N, Ozawa S, Sawada J. Sai K, et al. Pharmacogenetics. 2003 Dec;13(12):741-57. doi: 10.1097/00008571-200312000-00005. Pharmacogenetics. 2003. PMID: 14646693

10

Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population.

Fukushima-Uesaka H, Saito Y, Watanabe H, Shiseki K, Saeki M, Nakamura T, Kurose K, Sai K, Komamura K, Ueno K, Kamakura S, Kitakaze M, Hanai S, Nakajima T, Matsumoto K, Saito H, Goto Y, Kimura H, Katoh M, Sugai K, Minami N, Shirao K, Tamura T, Yamamoto N, Minami H, Ohtsu A, Yoshida T, Saijo N, Kitamura Y, Kamatani N, Ozawa S, Sawada J. Fukushima-Uesaka H, et al. Among authors: sai k. Hum Mutat. 2004 Jan;23(1):100. doi: 10.1002/humu.9210. Hum Mutat. 2004. PMID: 14695543

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