Bradley MN - Search Results

1

Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE.

Bradley MN, Hong C, Chen M, Joseph SB, Wilpitz DC, Wang X, Lusis AJ, Collins A, Hseuh WA, Collins JL, Tangirala RK, Tontonoz P. Bradley MN, et al. J Clin Invest. 2007 Aug;117(8):2337-46. doi: 10.1172/JCI31909. J Clin Invest. 2007. PMID: 17657314 Free PMC article.

2

Phosphorylation of the liver X receptors.

Chen M, Bradley MN, Beaven SW, Tontonoz P. Chen M, et al. Among authors: bradley mn. FEBS Lett. 2006 Sep 4;580(20):4835-41. doi: 10.1016/j.febslet.2006.07.074. Epub 2006 Aug 4. FEBS Lett. 2006. PMID: 16904112 Free article.

3

LXR-dependent gene expression is important for macrophage survival and the innate immune response.

Joseph SB, Bradley MN, Castrillo A, Bruhn KW, Mak PA, Pei L, Hogenesch J, O'connell RM, Cheng G, Saez E, Miller JF, Tontonoz P. Joseph SB, et al. Among authors: bradley mn. Cell. 2004 Oct 15;119(2):299-309. doi: 10.1016/j.cell.2004.09.032. Cell. 2004. PMID: 15479645 Free article.

4

The arginase II gene is an anti-inflammatory target of liver X receptor in macrophages.

Marathe C, Bradley MN, Hong C, Lopez F, Ruiz de Galarreta CM, Tontonoz P, Castrillo A. Marathe C, et al. Among authors: bradley mn. J Biol Chem. 2006 Oct 27;281(43):32197-206. doi: 10.1074/jbc.M605237200. Epub 2006 Aug 30. J Biol Chem. 2006. PMID: 16943198 Free article.

5

LXR signaling couples sterol metabolism to proliferation in the acquired immune response.

Bensinger SJ, Bradley MN, Joseph SB, Zelcer N, Janssen EM, Hausner MA, Shih R, Parks JS, Edwards PA, Jamieson BD, Tontonoz P. Bensinger SJ, et al. Among authors: bradley mn. Cell. 2008 Jul 11;134(1):97-111. doi: 10.1016/j.cell.2008.04.052. Cell. 2008. PMID: 18614014 Free PMC article.

6

Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARgamma-/-, PPARdelta-/-, PPARgammadelta-/-, or LXRalphabeta-/- bone marrow.

Marathe C, Bradley MN, Hong C, Chao L, Wilpitz D, Salazar J, Tontonoz P. Marathe C, et al. Among authors: bradley mn. J Lipid Res. 2009 Feb;50(2):214-24. doi: 10.1194/jlr.M800189-JLR200. Epub 2008 Sep 4. J Lipid Res. 2009. PMID: 18772483 Free PMC article.

7

T0901317, an LXR agonist, augments PKA-induced vascular cell calcification.

Hsu JJ, Lu J, Huang MS, Geng Y, Sage AP, Bradley MN, Tontonoz P, Demer LL, Tintut Y. Hsu JJ, et al. Among authors: bradley mn. FEBS Lett. 2009 Apr 17;583(8):1344-8. doi: 10.1016/j.febslet.2009.03.039. Epub 2009 Mar 25. FEBS Lett. 2009. PMID: 19327357 Free PMC article.

8

LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression.

Feig JE, Pineda-Torra I, Sanson M, Bradley MN, Vengrenyuk Y, Bogunovic D, Gautier EL, Rubinstein D, Hong C, Liu J, Wu C, van Rooijen N, Bhardwaj N, Garabedian M, Tontonoz P, Fisher EA. Feig JE, et al. Among authors: bradley mn. J Clin Invest. 2010 Dec;120(12):4415-24. doi: 10.1172/JCI38911. J Clin Invest. 2010. PMID: 21041949 Free PMC article.

9

Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target.

Hong C, Walczak R, Dhamko H, Bradley MN, Marathe C, Boyadjian R, Salazar JV, Tontonoz P. Hong C, et al. Among authors: bradley mn. J Lipid Res. 2011 Mar;52(3):531-9. doi: 10.1194/jlr.M010686. Epub 2010 Dec 27. J Lipid Res. 2011. PMID: 21187453 Free PMC article.

10

TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis.

Naiki Y, Sorrentino R, Wong MH, Michelsen KS, Shimada K, Chen S, Yilmaz A, Slepenkin A, Schröder NW, Crother TR, Bulut Y, Doherty TM, Bradley M, Shaposhnik Z, Peterson EM, Tontonoz P, Shah PK, Arditi M. Naiki Y, et al. J Immunol. 2008 Nov 15;181(10):7176-85. doi: 10.4049/jimmunol.181.10.7176. J Immunol. 2008. PMID: 18981139 Free PMC article.

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