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Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis.
Büning C, Schmidt HH, Molnar T, De Jong DJ, Fiedler T, Bühner S, Sturm A, Baumgart DC, Nagy F, Lonovics J, Drenth JP, Landt O, Nickel R, Büttner J, Lochs H, Witt H. Büning C, et al. Among authors: lochs h. Aliment Pharmacol Ther. 2007 Oct 1;26(7):1025-33. doi: 10.1111/j.1365-2036.2007.03446.x. Aliment Pharmacol Ther. 2007. PMID: 17877509
DLG5 variants in inflammatory bowel disease.
Büning C, Geerdts L, Fiedler T, Gentz E, Pitre G, Reuter W, Luck W, Buhner S, Molnar T, Nagy F, Lonovics J, Dignass A, Landt O, Nickel R, Genschel J, Lochs H, Schmidt HH, Witt H. Büning C, et al. Among authors: lochs h. Am J Gastroenterol. 2006 Apr;101(4):786-92. doi: 10.1111/j.1572-0241.2006.00431.x. Epub 2006 Feb 22. Am J Gastroenterol. 2006. PMID: 16494592
Conventional therapy for Crohn's disease.
Büning C, Lochs H. Büning C, et al. Among authors: lochs h. World J Gastroenterol. 2006 Aug 14;12(30):4794-806. doi: 10.3748/wjg.v12.i30.4794. World J Gastroenterol. 2006. PMID: 16937460 Free PMC article. Review.
No association of the CARD8 (TUCAN) c.30T>A (p.C10X) variant with Crohn's disease: a study in 3 independent European cohorts.
Büning C, Schmidt HH, Molnár T, Drenth JP, Fiedler T, Gentz E, Todorov T, Baumgart DC, Sturm A, Nagy F, Lonovics J, de Jong DJ, Landt O, Kage A, Nickel R, Büttner J, Lochs H, Witt H. Büning C, et al. Among authors: lochs h. Inflamm Bowel Dis. 2008 Mar;14(3):332-7. doi: 10.1002/ibd.20337. Inflamm Bowel Dis. 2008. PMID: 18092344
The c.1-260C>T promoter variant of CD14 but not the c.896A>G (p.D299G) variant of toll-like receptor 4 (TLR4) genes is associated with inflammatory bowel disease.
Baumgart DC, Buning C, Geerdts L, Schmidt HH, Genschel J, Fiedler T, Gentz E, Molnar T, Nagy F, Lonovics J, Lochs H, Wiedenmann B, Nickel R, Witt H, Dignass A. Baumgart DC, et al. Among authors: lochs h. Digestion. 2007;76(3-4):196-202. doi: 10.1159/000112646. Epub 2007 Dec 21. Digestion. 2007. PMID: 18174680
A study in three European IBD cohorts confirms that the ATG16L1 c.898A>G (p.Thr300Ala) variant is a susceptibility factor for Crohn's disease.
Büning C, Durmus T, Molnar T, de Jong DJ, Drenth JP, Fiedler T, Gentz E, Todorov T, Haas V, Buhner S, Sturm A, Baumgart DC, Nagy F, Lonovics J, Landt O, Kage A, Büning H, Nickel R, Büttner J, Lochs H, Schmidt HH, Witt H. Büning C, et al. Among authors: lochs h. J Crohns Colitis. 2007 Dec;1(2):70-6. doi: 10.1016/j.crohns.2007.08.001. Epub 2007 Sep 27. J Crohns Colitis. 2007. PMID: 21172187
316 results