Suh N - Search Results

1

CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer binding protein alpha.

Koschmieder S, D'Alò F, Radomska H, Schöneich C, Chang JS, Konopleva M, Kobayashi S, Levantini E, Suh N, Di Ruscio A, Voso MT, Watt JC, Santhanam R, Sargin B, Kantarjian H, Andreeff M, Sporn MB, Perrotti D, Berdel WE, Müller-Tidow C, Serve H, Tenen DG. Koschmieder S, et al. Among authors: suh n. Blood. 2007 Nov 15;110(10):3695-705. doi: 10.1182/blood-2006-11-058941. Epub 2007 Aug 1. Blood. 2007. PMID: 17671235 Free PMC article. Clinical Trial.

2

Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia.

Konopleva M, Tsao T, Ruvolo P, Stiouf I, Estrov Z, Leysath CE, Zhao S, Harris D, Chang S, Jackson CE, Munsell M, Suh N, Gribble G, Honda T, May WS, Sporn MB, Andreeff M. Konopleva M, et al. Among authors: suh n. Blood. 2002 Jan 1;99(1):326-35. doi: 10.1182/blood.v99.1.326. Blood. 2002. PMID: 11756188 Free article.

3

The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti-multiple myeloma (MM) activity and overcome bortezomib resistance.

Chauhan D, Li G, Podar K, Hideshima T, Shringarpure R, Catley L, Mitsiades C, Munshi N, Tai YT, Suh N, Gribble GW, Honda T, Schlossman R, Richardson P, Sporn MB, Anderson KC. Chauhan D, et al. Among authors: suh n. Blood. 2004 Apr 15;103(8):3158-66. doi: 10.1182/blood-2003-08-2873. Epub 2003 Dec 11. Blood. 2004. PMID: 15070698 Free article.

4

The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells.

Stadheim TA, Suh N, Ganju N, Sporn MB, Eastman A. Stadheim TA, et al. Among authors: suh n. J Biol Chem. 2002 May 10;277(19):16448-55. doi: 10.1074/jbc.M108974200. Epub 2002 Mar 5. J Biol Chem. 2002. PMID: 11880365 Free article.

5

The synthetic triterpenoid CDDO-imidazolide induces monocytic differentiation by activating the Smad and ERK signaling pathways in HL60 leukemia cells.

Ji Y, Lee HJ, Goodman C, Uskokovic M, Liby K, Sporn M, Suh N. Ji Y, et al. Among authors: suh n. Mol Cancer Ther. 2006 Jun;5(6):1452-8. doi: 10.1158/1535-7163.MCT-06-0136. Mol Cancer Ther. 2006. PMID: 16818503

6

Retraction: The triterpenoid CDDO-Imidazolide induces apoptosis and enhances fludarabine-induced apoptosis of CLL B-cells.

Pedersen IM, Zapata JM, Samuel T, Scott FL, Salvesen GS, Honda T, Gribble GW, Suh N, Sporn MB, Kipps TJ, Reed JC. Pedersen IM, et al. Among authors: suh n. Blood. 2004 Aug 15;104(4):932. doi: 10.1182/blood-2003-11-3774. Epub 2004 Jan 22. Blood. 2004. PMID: 14739219 Free article. Retracted. No abstract available.

7

Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells.

Kim KB, Lotan R, Yue P, Sporn MB, Suh N, Gribble GW, Honda T, Wu GS, Hong WK, Sun SY. Kim KB, et al. Among authors: suh n. Mol Cancer Ther. 2002 Jan;1(3):177-84. Mol Cancer Ther. 2002. PMID: 12467212

8

Synthetic triterpenoids activate a pathway for apoptosis in AML cells involving downregulation of FLIP and sensitization to TRAIL.

Suh WS, Kim YS, Schimmer AD, Kitada S, Minden M, Andreeff M, Suh N, Sporn M, Reed JC. Suh WS, et al. Among authors: suh n. Leukemia. 2003 Nov;17(11):2122-9. doi: 10.1038/sj.leu.2403112. Leukemia. 2003. PMID: 12931220

9

Peroxisome proliferator-activated receptor-gamma-independent repression of collagenase gene expression by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and prostaglandin 15-deoxy-delta(12,14) J2: a role for Smad signaling.

Mix KS, Coon CI, Rosen ED, Suh N, Sporn MB, Brinckerhoff CE. Mix KS, et al. Among authors: suh n. Mol Pharmacol. 2004 Feb;65(2):309-18. doi: 10.1124/mol.65.2.309. Mol Pharmacol. 2004. PMID: 14742672

10

A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer.

So JY, Lin JJ, Wahler J, Liby KT, Sporn MB, Suh N. So JY, et al. Among authors: suh n. PLoS One. 2014 Sep 17;9(9):e107616. doi: 10.1371/journal.pone.0107616. eCollection 2014. PLoS One. 2014. PMID: 25229616 Free PMC article.

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