Blumenschein WM - Search Results

1

Development, cytokine profile and function of human interleukin 17-producing helper T cells.

Wilson NJ, Boniface K, Chan JR, McKenzie BS, Blumenschein WM, Mattson JD, Basham B, Smith K, Chen T, Morel F, Lecron JC, Kastelein RA, Cua DJ, McClanahan TK, Bowman EP, de Waal Malefyt R. Wilson NJ, et al. Among authors: blumenschein wm. Nat Immunol. 2007 Sep;8(9):950-7. doi: 10.1038/ni1497. Epub 2007 Aug 5. Nat Immunol. 2007. PMID: 17676044

2

TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology.

McGeachy MJ, Bak-Jensen KS, Chen Y, Tato CM, Blumenschein W, McClanahan T, Cua DJ. McGeachy MJ, et al. Nat Immunol. 2007 Dec;8(12):1390-7. doi: 10.1038/ni1539. Epub 2007 Nov 11. Nat Immunol. 2007. PMID: 17994024

3

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo.

McGeachy MJ, Chen Y, Tato CM, Laurence A, Joyce-Shaikh B, Blumenschein WM, McClanahan TK, O'Shea JJ, Cua DJ. McGeachy MJ, et al. Among authors: blumenschein wm. Nat Immunol. 2009 Mar;10(3):314-24. doi: 10.1038/ni.1698. Epub 2009 Feb 1. Nat Immunol. 2009. PMID: 19182808 Free PMC article.

4

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling.

Boniface K, Bak-Jensen KS, Li Y, Blumenschein WM, McGeachy MJ, McClanahan TK, McKenzie BS, Kastelein RA, Cua DJ, de Waal Malefyt R. Boniface K, et al. Among authors: blumenschein wm. J Exp Med. 2009 Mar 16;206(3):535-48. doi: 10.1084/jem.20082293. Epub 2009 Mar 9. J Exp Med. 2009. PMID: 19273625 Free PMC article.

5

Human Th17 cells comprise heterogeneous subsets including IFN-gamma-producing cells with distinct properties from the Th1 lineage.

Boniface K, Blumenschein WM, Brovont-Porth K, McGeachy MJ, Basham B, Desai B, Pierce R, McClanahan TK, Sadekova S, de Waal Malefyt R. Boniface K, et al. Among authors: blumenschein wm. J Immunol. 2010 Jul 1;185(1):679-87. doi: 10.4049/jimmunol.1000366. Epub 2010 May 28. J Immunol. 2010. PMID: 20511558

6

Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2.

Chen Y, Haines CJ, Gutcher I, Hochweller K, Blumenschein WM, McClanahan T, Hämmerling G, Li MO, Cua DJ, McGeachy MJ. Chen Y, et al. Among authors: blumenschein wm. Immunity. 2011 Mar 25;34(3):409-21. doi: 10.1016/j.immuni.2011.02.011. Immunity. 2011. PMID: 21435588 Free article.

7

Autoimmune memory T helper 17 cell function and expansion are dependent on interleukin-23.

Haines CJ, Chen Y, Blumenschein WM, Jain R, Chang C, Joyce-Shaikh B, Porth K, Boniface K, Mattson J, Basham B, Anderton SM, McClanahan TK, Sadekova S, Cua DJ, McGeachy MJ. Haines CJ, et al. Among authors: blumenschein wm. Cell Rep. 2013 May 30;3(5):1378-88. doi: 10.1016/j.celrep.2013.03.035. Epub 2013 Apr 25. Cell Rep. 2013. PMID: 23623497 Free article.

8

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation.

Murphy CA, Langrish CL, Chen Y, Blumenschein W, McClanahan T, Kastelein RA, Sedgwick JD, Cua DJ. Murphy CA, et al. J Exp Med. 2003 Dec 15;198(12):1951-7. doi: 10.1084/jem.20030896. Epub 2003 Dec 8. J Exp Med. 2003. PMID: 14662908 Free PMC article.

9

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6.

Yen D, Cheung J, Scheerens H, Poulet F, McClanahan T, McKenzie B, Kleinschek MA, Owyang A, Mattson J, Blumenschein W, Murphy E, Sathe M, Cua DJ, Kastelein RA, Rennick D. Yen D, et al. J Clin Invest. 2006 May;116(5):1310-6. doi: 10.1172/JCI21404. J Clin Invest. 2006. PMID: 16670770 Free PMC article.

10

Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis.

Chen Y, Langrish CL, McKenzie B, Joyce-Shaikh B, Stumhofer JS, McClanahan T, Blumenschein W, Churakovsa T, Low J, Presta L, Hunter CA, Kastelein RA, Cua DJ. Chen Y, et al. J Clin Invest. 2006 May;116(5):1317-26. doi: 10.1172/JCI25308. J Clin Invest. 2006. PMID: 16670771 Free PMC article.

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