Edmunds T - Search Results

1

Development of a simple and rapid method for producing non-fucosylated oligomannose containing antibodies with increased effector function.

Zhou Q, Shankara S, Roy A, Qiu H, Estes S, McVie-Wylie A, Culm-Merdek K, Park A, Pan C, Edmunds T. Zhou Q, et al. Among authors: edmunds t. Biotechnol Bioeng. 2008 Feb 15;99(3):652-65. doi: 10.1002/bit.21598. Biotechnol Bioeng. 2008. PMID: 17680659

2

In vitro and in vivo evaluation of a non-carbohydrate targeting platform for lysosomal proteins.

Stefano JE, Hou L, Honey D, Kyazike J, Park A, Zhou Q, Pan CQ, Edmunds T. Stefano JE, et al. Among authors: edmunds t. J Control Release. 2009 Apr 17;135(2):113-8. doi: 10.1016/j.jconrel.2008.12.006. Epub 2008 Dec 24. J Control Release. 2009. PMID: 19146893

3

Effect of genetic background on glycosylation heterogeneity in human antithrombin produced in the mammary gland of transgenic goats.

Zhou Q, Kyazike J, Echelard Y, Meade HM, Higgins E, Cole ES, Edmunds T. Zhou Q, et al. Among authors: edmunds t. J Biotechnol. 2005 Apr 20;117(1):57-72. doi: 10.1016/j.jbiotec.2005.01.001. J Biotechnol. 2005. PMID: 15831248

4

Strategies for Neoglycan conjugation to human acid α-glucosidase.

Zhou Q, Stefano JE, Harrahy J, Finn P, Avila L, Kyazike J, Wei R, Van Patten SM, Gotschall R, Zheng X, Zhu Y, Edmunds T, Pan CQ. Zhou Q, et al. Among authors: edmunds t. Bioconjug Chem. 2011 Apr 20;22(4):741-51. doi: 10.1021/bc1005416. Epub 2011 Mar 18. Bioconjug Chem. 2011. PMID: 21417264

5

Activation of human acid sphingomyelinase through modification or deletion of C-terminal cysteine.

Qiu H, Edmunds T, Baker-Malcolm J, Karey KP, Estes S, Schwarz C, Hughes H, Van Patten SM. Qiu H, et al. Among authors: edmunds t. J Biol Chem. 2003 Aug 29;278(35):32744-52. doi: 10.1074/jbc.M303022200. Epub 2003 Jun 11. J Biol Chem. 2003. PMID: 12801930 Free article.

6

Effect of mannose chain length on targeting of glucocerebrosidase for enzyme replacement therapy of Gaucher disease.

Van Patten SM, Hughes H, Huff MR, Piepenhagen PA, Waire J, Qiu H, Ganesa C, Reczek D, Ward PV, Kutzko JP, Edmunds T. Van Patten SM, et al. Among authors: edmunds t. Glycobiology. 2007 May;17(5):467-78. doi: 10.1093/glycob/cwm008. Epub 2007 Jan 24. Glycobiology. 2007. PMID: 17251309

7

Impact of cysteine variants on the structure, activity, and stability of recombinant human α-galactosidase A.

Qiu H, Honey DM, Kingsbury JS, Park A, Boudanova E, Wei RR, Pan CQ, Edmunds T. Qiu H, et al. Among authors: edmunds t. Protein Sci. 2015 Sep;24(9):1401-11. doi: 10.1002/pro.2719. Epub 2015 Jul 14. Protein Sci. 2015. PMID: 26044846 Free PMC article.

8

X-ray and biochemical analysis of N370S mutant human acid β-glucosidase.

Wei RR, Hughes H, Boucher S, Bird JJ, Guziewicz N, Van Patten SM, Qiu H, Pan CQ, Edmunds T. Wei RR, et al. Among authors: edmunds t. J Biol Chem. 2011 Jan 7;286(1):299-308. doi: 10.1074/jbc.M110.150433. Epub 2010 Oct 27. J Biol Chem. 2011. PMID: 20980263 Free PMC article.

9

Structures of a pan-specific antagonist antibody complexed to different isoforms of TGFβ reveal structural plasticity of antibody-antigen interactions.

Moulin A, Mathieu M, Lawrence C, Bigelow R, Levine M, Hamel C, Marquette JP, Le Parc J, Loux C, Ferrari P, Capdevila C, Dumas J, Dumas B, Rak A, Bird J, Qiu H, Pan CQ, Edmunds T, Wei RR. Moulin A, et al. Among authors: edmunds t. Protein Sci. 2014 Dec;23(12):1698-707. doi: 10.1002/pro.2548. Epub 2014 Sep 26. Protein Sci. 2014. PMID: 25209176 Free PMC article.

10

N-linked oligosaccharide analysis of glycoprotein bands from isoelectric focusing gels.

Zhou Q, Park SH, Boucher S, Higgins E, Lee K, Edmunds T. Zhou Q, et al. Among authors: edmunds t. Anal Biochem. 2004 Dec 1;335(1):10-6. doi: 10.1016/j.ab.2004.07.028. Anal Biochem. 2004. PMID: 15519566

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