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The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib.
Hantschel O, Rix U, Schmidt U, Bürckstümmer T, Kneidinger M, Schütze G, Colinge J, Bennett KL, Ellmeier W, Valent P, Superti-Furga G. Hantschel O, et al. Among authors: ellmeier w. Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13283-8. doi: 10.1073/pnas.0702654104. Epub 2007 Aug 7. Proc Natl Acad Sci U S A. 2007. PMID: 17684099 Free PMC article.
Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors.
Schmidt U, van den Akker E, Parren-van Amelsvoort M, Litos G, de Bruijn M, Gutiérrez L, Hendriks RW, Ellmeier W, Löwenberg B, Beug H, von Lindern M. Schmidt U, et al. Among authors: ellmeier w. J Exp Med. 2004 Mar 15;199(6):785-95. doi: 10.1084/jem.20031109. Epub 2004 Mar 8. J Exp Med. 2004. PMID: 15007095 Free PMC article.
The role of Tec family kinases in myeloid cells.
Schmidt U, Boucheron N, Unger B, Ellmeier W. Schmidt U, et al. Among authors: ellmeier w. Int Arch Allergy Immunol. 2004 May;134(1):65-78. doi: 10.1159/000078339. Epub 2004 May 4. Int Arch Allergy Immunol. 2004. PMID: 15133303 Review.
The effects of dasatinib on IgE receptor-dependent activation and histamine release in human basophils.
Kneidinger M, Schmidt U, Rix U, Gleixner KV, Vales A, Baumgartner C, Lupinek C, Weghofer M, Bennett KL, Herrmann H, Schebesta A, Thomas WR, Vrtala S, Valenta R, Lee FY, Ellmeier W, Superti-Furga G, Valent P. Kneidinger M, et al. Among authors: ellmeier w. Blood. 2008 Mar 15;111(6):3097-107. doi: 10.1182/blood-2007-08-104372. Epub 2008 Jan 7. Blood. 2008. PMID: 18180381 Free article.
The protein tyrosine kinase Tec regulates mast cell function.
Schmidt U, Abramova A, Boucheron N, Eckelhart E, Schebesta A, Bilic I, Kneidinger M, Unger B, Hammer M, Sibilia M, Valent P, Ellmeier W. Schmidt U, et al. Among authors: ellmeier w. Eur J Immunol. 2009 Nov;39(11):3228-38. doi: 10.1002/eji.200838839. Eur J Immunol. 2009. PMID: 19688741 Free article.
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset.
Boucheron N, Sharif O, Schebesta A, Croxford A, Raberger J, Schmidt U, Vigl B, Bauer J, Bankoti R, Lassmann H, Epstein MM, Knapp S, Waisman A, Ellmeier W. Boucheron N, et al. Among authors: ellmeier w. J Immunol. 2010 Nov 1;185(9):5111-9. doi: 10.4049/jimmunol.1001734. Epub 2010 Sep 24. J Immunol. 2010. PMID: 20870948
96 results