Bubert C - Search Results

1

3,17-disubstituted 2-alkylestra-1,3,5(10)-trien-3-ol derivatives: synthesis, in vitro and in vivo anticancer activity.

Bubert C, Leese MP, Mahon MF, Ferrandis E, Regis-Lydi S, Kasprzyk PG, Newman SP, Ho YT, Purohit A, Reed MJ, Potter BV. Bubert C, et al. J Med Chem. 2007 Sep 6;50(18):4431-43. doi: 10.1021/jm070405v. Epub 2007 Aug 15. J Med Chem. 2007. PMID: 17696419

2

First dual aromatase-steroid sulfatase inhibitors.

Woo LW, Sutcliffe OB, Bubert C, Grasso A, Chander SK, Purohit A, Reed MJ, Potter BV. Woo LW, et al. Among authors: bubert c. J Med Chem. 2003 Jul 17;46(15):3193-6. doi: 10.1021/jm034033b. J Med Chem. 2003. PMID: 12852749

3

E-ring modified steroids as novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Fischer DS, Allan GM, Bubert C, Vicker N, Smith A, Tutill HJ, Purohit A, Wood L, Packham G, Mahon MF, Reed MJ, Potter BV. Fischer DS, et al. Among authors: bubert c. J Med Chem. 2005 Sep 8;48(18):5749-70. doi: 10.1021/jm050348a. J Med Chem. 2005. PMID: 16134943

4

Modification of estrone at the 6, 16, and 17 positions: novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Allan GM, Lawrence HR, Cornet J, Bubert C, Fischer DS, Vicker N, Smith A, Tutill HJ, Purohit A, Day JM, Mahon MF, Reed MJ, Potter BV. Allan GM, et al. Among authors: bubert c. J Med Chem. 2006 Feb 23;49(4):1325-45. doi: 10.1021/jm050830t. J Med Chem. 2006. PMID: 16480268

5

Dual aromatase-steroid sulfatase inhibitors.

Woo LW, Bubert C, Sutcliffe OB, Smith A, Chander SK, Mahon MF, Purohit A, Reed MJ, Potter BV. Woo LW, et al. Among authors: bubert c. J Med Chem. 2007 Jul 26;50(15):3540-60. doi: 10.1021/jm061462b. Epub 2007 Jun 20. J Med Chem. 2007. PMID: 17580845

6

Synthesis of aromatase inhibitors and dual aromatase steroid sulfatase inhibitors by linking an arylsulfamate motif to 4-(4H-1,2,4-triazol-4-ylamino)benzonitrile: SAR, crystal structures, in vitro and in vivo activities.

Bubert C, Woo LW, Sutcliffe OB, Mahon MF, Chander SK, Purohit A, Reed MJ, Potter BV. Bubert C, et al. ChemMedChem. 2008 Nov;3(11):1708-30. doi: 10.1002/cmdc.200800164. ChemMedChem. 2008. PMID: 18816537

7

Effects of C-17 heterocyclic substituents on the anticancer activity of 2-ethylestra-1,3,5(10)-triene-3-O-sulfamates: synthesis, in vitro evaluation and computational modelling.

Jourdan F, Bubert C, Leese MP, Smith A, Ferrandis E, Regis-Lydi S, Newman SP, Purohit A, Reed MJ, Potter BV. Jourdan F, et al. Among authors: bubert c. Org Biomol Chem. 2008 Nov 21;6(22):4108-19. doi: 10.1039/b810300c. Epub 2008 Sep 22. Org Biomol Chem. 2008. PMID: 18972041

8

Synthesis and structure-activity relationship studies of derivatives of the dual aromatase-sulfatase inhibitor 4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl sulfamate.

Woo LW, Wood PM, Bubert C, Thomas MP, Purohit A, Potter BV. Woo LW, et al. Among authors: bubert c. ChemMedChem. 2013 May;8(5):779-99. doi: 10.1002/cmdc.201300015. Epub 2013 Mar 11. ChemMedChem. 2013. PMID: 23495205 Free PMC article.

9

Hybrid dual aromatase-steroid sulfatase inhibitors with exquisite picomolar inhibitory activity.

Woo LW, Bubert C, Purohit A, Potter BV. Woo LW, et al. Among authors: bubert c. ACS Med Chem Lett. 2010 Dec 29;2(3):243-7. doi: 10.1021/ml100273k. eCollection 2011 Mar 10. ACS Med Chem Lett. 2010. PMID: 24900302 Free PMC article.

10

Novel, potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Allan GM, Bubert C, Vicker N, Smith A, Tutill HJ, Purohit A, Reed MJ, Potter BV. Allan GM, et al. Among authors: bubert c. Mol Cell Endocrinol. 2006 Mar 27;248(1-2):204-7. doi: 10.1016/j.mce.2005.10.021. Epub 2005 Dec 7. Mol Cell Endocrinol. 2006. PMID: 16337736

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

15 results

Search Page

Filters