Franchi L - Search Results

1

Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages.

Suzuki T, Franchi L, Toma C, Ashida H, Ogawa M, Yoshikawa Y, Mimuro H, Inohara N, Sasakawa C, Nuñez G. Suzuki T, et al. Among authors: franchi l. PLoS Pathog. 2007 Aug 10;3(8):e111. doi: 10.1371/journal.ppat.0030111. PLoS Pathog. 2007. PMID: 17696608 Free PMC article.

2

Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ.

Suzuki S, Franchi L, He Y, Muñoz-Planillo R, Mimuro H, Suzuki T, Sasakawa C, Núñez G. Suzuki S, et al. Among authors: franchi l. PLoS Pathog. 2014 Feb 6;10(2):e1003926. doi: 10.1371/journal.ppat.1003926. eCollection 2014 Feb. PLoS Pathog. 2014. PMID: 24516390 Free PMC article.

3

Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages.

Suzuki S, Mimuro H, Kim M, Ogawa M, Ashida H, Toyotome T, Franchi L, Suzuki M, Sanada T, Suzuki T, Tsutsui H, Núñez G, Sasakawa C. Suzuki S, et al. Among authors: franchi l. Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):E4254-63. doi: 10.1073/pnas.1324021111. Epub 2014 Sep 22. Proc Natl Acad Sci U S A. 2014. PMID: 25246571 Free PMC article.

4

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages.

Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozören N, Jagirdar R, Inohara N, Vandenabeele P, Bertin J, Coyle A, Grant EP, Núñez G. Franchi L, et al. Nat Immunol. 2006 Jun;7(6):576-82. doi: 10.1038/ni1346. Epub 2006 Apr 30. Nat Immunol. 2006. PMID: 16648852

5

Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation.

Franchi L, Stoolman J, Kanneganti TD, Verma A, Ramphal R, Núñez G. Franchi L, et al. Eur J Immunol. 2007 Nov;37(11):3030-9. doi: 10.1002/eji.200737532. Eur J Immunol. 2007. PMID: 17935074 Free article.

6

Pathogenic Vibrio activate NLRP3 inflammasome via cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-kappa B signaling.

Toma C, Higa N, Koizumi Y, Nakasone N, Ogura Y, McCoy AJ, Franchi L, Uematsu S, Sagara J, Taniguchi S, Tsutsui H, Akira S, Tschopp J, Núñez G, Suzuki T. Toma C, et al. Among authors: franchi l. J Immunol. 2010 May 1;184(9):5287-97. doi: 10.4049/jimmunol.0903536. Epub 2010 Mar 26. J Immunol. 2010. PMID: 20348425

7

The protein kinase PKR is critical for LPS-induced iNOS production but dispensable for inflammasome activation in macrophages.

He Y, Franchi L, Núñez G. He Y, et al. Among authors: franchi l. Eur J Immunol. 2013 May;43(5):1147-52. doi: 10.1002/eji.201243187. Epub 2013 Mar 15. Eur J Immunol. 2013. PMID: 23401008 Free PMC article.

8

Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes.

Ozören N, Masumoto J, Franchi L, Kanneganti TD, Body-Malapel M, Ertürk I, Jagirdar R, Zhu L, Inohara N, Bertin J, Coyle A, Grant EP, Núñez G. Ozören N, et al. Among authors: franchi l. J Immunol. 2006 Apr 1;176(7):4337-42. doi: 10.4049/jimmunol.176.7.4337. J Immunol. 2006. PMID: 16547271

9

Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA.

Kanneganti TD, Body-Malapel M, Amer A, Park JH, Whitfield J, Franchi L, Taraporewala ZF, Miller D, Patton JT, Inohara N, Núñez G. Kanneganti TD, et al. Among authors: franchi l. J Biol Chem. 2006 Dec 1;281(48):36560-8. doi: 10.1074/jbc.M607594200. Epub 2006 Sep 28. J Biol Chem. 2006. PMID: 17008311 Free article.

10

Caspase-1 inflammasomes in infection and inflammation.

Lamkanfi M, Kanneganti TD, Franchi L, Núñez G. Lamkanfi M, et al. Among authors: franchi l. J Leukoc Biol. 2007 Aug;82(2):220-5. doi: 10.1189/jlb.1206756. Epub 2007 Apr 18. J Leukoc Biol. 2007. PMID: 17442855 Free article. Review.

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