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Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimics.
Clinch K, Evans GB, Fröhlich RF, Gulab SA, Gutierrez JA, Mason JM, Schramm VL, Tyler PC, Woolhouse AD. Clinch K, et al. Among authors: mason jm. Bioorg Med Chem. 2012 Sep 1;20(17):5181-7. doi: 10.1016/j.bmc.2012.07.006. Epub 2012 Jul 14. Bioorg Med Chem. 2012. PMID: 22854195 Free PMC article.
Oligonucleotide transition state analogues of saporin L3.
Mason JM, Yuan H, Evans GB, Tyler PC, Du Q, Schramm VL. Mason JM, et al. Eur J Med Chem. 2017 Feb 15;127:793-809. doi: 10.1016/j.ejmech.2016.10.059. Epub 2016 Oct 27. Eur J Med Chem. 2017. PMID: 27823883 Free PMC article.
Immucillins in custom catalytic-site cavities.
Murkin AS, Clinch K, Mason JM, Tyler PC, Schramm VL. Murkin AS, et al. Among authors: mason jm. Bioorg Med Chem Lett. 2008 Nov 15;18(22):5900-3. doi: 10.1016/j.bmcl.2008.08.047. Epub 2008 Aug 19. Bioorg Med Chem Lett. 2008. PMID: 18778937 Free PMC article.
Biofilm Inhibition via Delivery of Novel Methylthioadenosine Nucleosidase Inhibitors from PVA-Tyramine Hydrogels while Supporting Mesenchymal Stromal Cell Viability.
Mutreja I, Warring SL, Lim KS, Swadi T, Clinch K, Mason JM, Sheen CR, Thompson DR, Ducati RG, Chambers ST, Evans GB, Gerth ML, Miller AG, Woodfield TBF. Mutreja I, et al. Among authors: mason jm. ACS Biomater Sci Eng. 2019 Feb 11;5(2):748-758. doi: 10.1021/acsbiomaterials.8b01141. Epub 2019 Jan 10. ACS Biomater Sci Eng. 2019. PMID: 33405836
407 results