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Splenic fibroblasts control marginal zone B cell movement and function via two distinct Notch2-dependent regulatory programs.
Allman A, Gaudette BT, Kelly S, Alouche N, Carrington LJ, Perkey E, Brandstadter JD, Outen R, Vanderbeck A, Lederer K, Zhou Y, Faryabi RB, Robertson TF, Burkhardt JK, Tikhonova A, Aifantis I, Scarpellino L, Koch U, Radtke F, Lütge M, De Martin A, Ludewig B, Tveriakhina L, Gossler A, Mosteiro L, Siebel CW, Gómez Atria D, Luther SA, Allman D, Maillard I. Allman A, et al. Among authors: luther sa. Immunity. 2024 Dec 25:S1074-7613(24)00567-3. doi: 10.1016/j.immuni.2024.12.003. Online ahead of print. Immunity. 2024. PMID: 39731910
Unique and redundant roles of mouse BCMA, TACI, BAFF, APRIL, and IL-6 in supporting antibody-producing cells in different tissues.
Eslami M, Schuepbach-Mallepell S, Diana D, Willen L, Kowalczyk-Quintas C, Desponds C, Peter B, Vigolo M, Renevey F, Donzé O, Luther SA, Yalkinoglu Ö, Alouche N, Schneider P. Eslami M, et al. Among authors: luther sa. Proc Natl Acad Sci U S A. 2024 Jul 16;121(29):e2404309121. doi: 10.1073/pnas.2404309121. Epub 2024 Jul 11. Proc Natl Acad Sci U S A. 2024. PMID: 38990948 Free PMC article.
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8+ T cells.
Corria-Osorio J, Carmona SJ, Stefanidis E, Andreatta M, Ortiz-Miranda Y, Muller T, Rota IA, Crespo I, Seijo B, Castro W, Jimenez-Luna C, Scarpellino L, Ronet C, Spill A, Lanitis E, Romero P, Luther SA, Irving M, Coukos G. Corria-Osorio J, et al. Among authors: luther sa. Nat Immunol. 2023 May;24(5):869-883. doi: 10.1038/s41590-023-01477-2. Epub 2023 Apr 20. Nat Immunol. 2023. PMID: 37081150 Free PMC article.
The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection.
Marx AF, Kallert SM, Brunner TM, Villegas JA, Geier F, Fixemer J, Abreu-Mota T, Reuther P, Bonilla WV, Fadejeva J, Kreutzfeldt M, Wagner I, Aparicio-Domingo P, Scarpellino L, Charmoy M, Utzschneider DT, Hagedorn C, Lu M, Cornille K, Stauffer K, Kreppel F, Merkler D, Zehn D, Held W, Luther SA, Löhning M, Pinschewer DD. Marx AF, et al. Among authors: luther sa. Immunity. 2023 Apr 11;56(4):813-828.e10. doi: 10.1016/j.immuni.2023.01.029. Epub 2023 Feb 20. Immunity. 2023. PMID: 36809763 Free article.
In and out: Leishmania metastasis by hijacking lymphatic system and migrating immune cells.
Jha B, Reverte M, Ronet C, Prevel F, Morgenthaler FD, Desponds C, Lye LF, Owens KL, Scarpellino L, Dubey LK, Sabine A, Petrova TV, Luther SA, Beverley SM, Fasel N. Jha B, et al. Among authors: luther sa. Front Cell Infect Microbiol. 2022 Aug 12;12:941860. doi: 10.3389/fcimb.2022.941860. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36034709 Free PMC article.
Multitier mechanics control stromal adaptations in the swelling lymph node.
Assen FP, Abe J, Hons M, Hauschild R, Shamipour S, Kaufmann WA, Costanzo T, Krens G, Brown M, Ludewig B, Hippenmeyer S, Heisenberg CP, Weninger W, Hannezo E, Luther SA, Stein JV, Sixt M. Assen FP, et al. Among authors: luther sa. Nat Immunol. 2022 Aug;23(8):1246-1255. doi: 10.1038/s41590-022-01257-4. Epub 2022 Jul 11. Nat Immunol. 2022. PMID: 35817845 Free PMC article.
ADAMTS18+ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels.
Bernier-Latmani J, Mauri C, Marcone R, Renevey F, Durot S, He L, Vanlandewijck M, Maclachlan C, Davanture S, Zamboni N, Knott GW, Luther SA, Betsholtz C, Delorenzi M, Brisken C, Petrova TV. Bernier-Latmani J, et al. Among authors: luther sa. Nat Commun. 2022 Jul 9;13(1):3983. doi: 10.1038/s41467-022-31571-2. Nat Commun. 2022. PMID: 35810168 Free PMC article.
88 results