Kliewer SA - Search Results

1

Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine.

Kim I, Ahn SH, Inagaki T, Choi M, Ito S, Guo GL, Kliewer SA, Gonzalez FJ. Kim I, et al. Among authors: kliewer sa. J Lipid Res. 2007 Dec;48(12):2664-72. doi: 10.1194/jlr.M700330-JLR200. Epub 2007 Aug 24. J Lipid Res. 2007. PMID: 17720959 Free article.

2

Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity.

Guo GL, Lambert G, Negishi M, Ward JM, Brewer HB Jr, Kliewer SA, Gonzalez FJ, Sinal CJ. Guo GL, et al. Among authors: kliewer sa. J Biol Chem. 2003 Nov 14;278(46):45062-71. doi: 10.1074/jbc.M307145200. Epub 2003 Aug 15. J Biol Chem. 2003. PMID: 12923173 Free article.

3

Enhanced acetaminophen toxicity by activation of the pregnane X receptor.

Guo GL, Moffit JS, Nicol CJ, Ward JM, Aleksunes LA, Slitt AL, Kliewer SA, Manautou JE, Gonzalez FJ. Guo GL, et al. Among authors: kliewer sa. Toxicol Sci. 2004 Dec;82(2):374-80. doi: 10.1093/toxsci/kfh286. Epub 2004 Sep 29. Toxicol Sci. 2004. PMID: 15456926

4

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis.

Inagaki T, Choi M, Moschetta A, Peng L, Cummins CL, McDonald JG, Luo G, Jones SA, Goodwin B, Richardson JA, Gerard RD, Repa JJ, Mangelsdorf DJ, Kliewer SA. Inagaki T, et al. Among authors: kliewer sa. Cell Metab. 2005 Oct;2(4):217-25. doi: 10.1016/j.cmet.2005.09.001. Cell Metab. 2005. PMID: 16213224 Free article.

5

FXR agonists and FGF15 reduce fecal bile acid excretion in a mouse model of bile acid malabsorption.

Jung D, Inagaki T, Gerard RD, Dawson PA, Kliewer SA, Mangelsdorf DJ, Moschetta A. Jung D, et al. Among authors: kliewer sa. J Lipid Res. 2007 Dec;48(12):2693-700. doi: 10.1194/jlr.M700351-JLR200. Epub 2007 Sep 6. J Lipid Res. 2007. PMID: 17823457 Free article.

6

Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor.

Inagaki T, Moschetta A, Lee YK, Peng L, Zhao G, Downes M, Yu RT, Shelton JM, Richardson JA, Repa JJ, Mangelsdorf DJ, Kliewer SA. Inagaki T, et al. Among authors: kliewer sa. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3920-5. doi: 10.1073/pnas.0509592103. Epub 2006 Feb 10. Proc Natl Acad Sci U S A. 2006. PMID: 16473946 Free PMC article.

7

Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis.

Lee YK, Schmidt DR, Cummins CL, Choi M, Peng L, Zhang Y, Goodwin B, Hammer RE, Mangelsdorf DJ, Kliewer SA. Lee YK, et al. Among authors: kliewer sa. Mol Endocrinol. 2008 Jun;22(6):1345-56. doi: 10.1210/me.2007-0565. Epub 2008 Mar 6. Mol Endocrinol. 2008. PMID: 18323469 Free PMC article.

8

Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner.

Li Y, Choi M, Suino K, Kovach A, Daugherty J, Kliewer SA, Xu HE. Li Y, et al. Among authors: kliewer sa. Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9505-10. doi: 10.1073/pnas.0501204102. Epub 2005 Jun 23. Proc Natl Acad Sci U S A. 2005. PMID: 15976031 Free PMC article.

9

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.

Kurosu H, Choi M, Ogawa Y, Dickson AS, Goetz R, Eliseenkova AV, Mohammadi M, Rosenblatt KP, Kliewer SA, Kuro-O M. Kurosu H, et al. Among authors: kliewer sa. J Biol Chem. 2007 Sep 14;282(37):26687-26695. doi: 10.1074/jbc.M704165200. Epub 2007 Jul 10. J Biol Chem. 2007. PMID: 17623664 Free PMC article.

10

Inhibition of growth hormone signaling by the fasting-induced hormone FGF21.

Inagaki T, Lin VY, Goetz R, Mohammadi M, Mangelsdorf DJ, Kliewer SA. Inagaki T, et al. Among authors: kliewer sa. Cell Metab. 2008 Jul;8(1):77-83. doi: 10.1016/j.cmet.2008.05.006. Cell Metab. 2008. PMID: 18585098 Free PMC article.

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