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Page 1
Histamine H3 receptor antagonists: from target identification to drug leads.
Bonaventure P, Letavic M, Dugovic C, Wilson S, Aluisio L, Pudiak C, Lord B, Mazur C, Kamme F, Nishino S, Carruthers N, Lovenberg T. Bonaventure P, et al. Biochem Pharmacol. 2007 Apr 15;73(8):1084-96. doi: 10.1016/j.bcp.2006.10.031. Epub 2006 Nov 3. Biochem Pharmacol. 2007. PMID: 17129577
Novel human histamine H(3) receptor antagonists.
Shah C, McAtee L, Breitenbucher JG, Rudolph D, Li X, Lovenberg TW, Mazur C, Wilson SJ, Carruthers NI. Shah C, et al. Among authors: lovenberg tw. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3309-12. doi: 10.1016/s0960-894x(02)00738-2. Bioorg Med Chem Lett. 2002. PMID: 12392739
Non-imidazole heterocyclic histamine H3 receptor antagonists.
Chai W, Breitenbucher JG, Kwok A, Li X, Wong V, Carruthers NI, Lovenberg TW, Mazur C, Wilson SJ, Axe FU, Jones TK. Chai W, et al. Among authors: lovenberg tw. Bioorg Med Chem Lett. 2003 May 19;13(10):1767-70. doi: 10.1016/s0960-894x(03)00299-3. Bioorg Med Chem Lett. 2003. PMID: 12729661
The first potent and selective non-imidazole human histamine H4 receptor antagonists.
Jablonowski JA, Grice CA, Chai W, Dvorak CA, Venable JD, Kwok AK, Ly KS, Wei J, Baker SM, Desai PJ, Jiang W, Wilson SJ, Thurmond RL, Karlsson L, Edwards JP, Lovenberg TW, Carruthers NI. Jablonowski JA, et al. Among authors: lovenberg tw. J Med Chem. 2003 Sep 11;46(19):3957-60. doi: 10.1021/jm0341047. J Med Chem. 2003. PMID: 12954048
Aplysamine-1 and related analogs as histamine H3 receptor antagonists.
Swanson DM, Wilson SJ, Boggs JD, Xiao W, Apodaca R, Barbier AJ, Lovenberg TW, Carruthers NI. Swanson DM, et al. Among authors: lovenberg tw. Bioorg Med Chem Lett. 2006 Feb 15;16(4):897-900. doi: 10.1016/j.bmcl.2005.11.003. Epub 2005 Nov 21. Bioorg Med Chem Lett. 2006. PMID: 16300945
Preparation and biological evaluation of indole, benzimidazole, and thienopyrrole piperazine carboxamides: potent human histamine h(4) antagonists.
Venable JD, Cai H, Chai W, Dvorak CA, Grice CA, Jablonowski JA, Shah CR, Kwok AK, Ly KS, Pio B, Wei J, Desai PJ, Jiang W, Nguyen S, Ling P, Wilson SJ, Dunford PJ, Thurmond RL, Lovenberg TW, Karlsson L, Carruthers NI, Edwards JP. Venable JD, et al. Among authors: lovenberg tw. J Med Chem. 2005 Dec 29;48(26):8289-98. doi: 10.1021/jm0502081. J Med Chem. 2005. PMID: 16366610
171 results