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Pre-organization of the core structure of E-selectin antagonists.
Schwizer D, Patton JT, Cutting B, Smieško M, Wagner B, Kato A, Weckerle C, Binder FP, Rabbani S, Schwardt O, Magnani JL, Ernst B. Schwizer D, et al. Chemistry. 2012 Jan 27;18(5):1342-51. doi: 10.1002/chem.201102884. Epub 2011 Dec 30. Chemistry. 2012. PMID: 22213563
Quinic acid derivatives as sialyl Lewis(x)-mimicking selectin inhibitors: design, synthesis, and crystal structure in complex with E-selectin.
Kaila N, Somers WS, Thomas BE, Thakker P, Janz K, DeBernardo S, Tam S, Moore WJ, Yang R, Wrona W, Bedard PW, Crommie D, Keith JC Jr, Tsao DH, Alvarez JC, Ni H, Marchese E, Patton JT, Magnani JL, Camphausen RT. Kaila N, et al. Among authors: patton jt. J Med Chem. 2005 Jun 30;48(13):4346-57. doi: 10.1021/jm050049l. J Med Chem. 2005. PMID: 15974587
A Readily Available, Highly Potent E-Selectin Antagonist.
Thoma G, Bänteli R, Jahnke W, Magnani JL, Patton JT. Thoma G, et al. Angew Chem Int Ed Engl. 2001 Oct 1;40(19):3644-3647. doi: 10.1002/1521-3773(20011001)40:19<3644::AID-ANIE3644>3.0.CO;2-S. Angew Chem Int Ed Engl. 2001. PMID: 11592208 No abstract available.
1,225 results