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The selectivity of protein kinase inhibitors: a further update.
Bain J, Plater L, Elliott M, Shpiro N, Hastie CJ, McLauchlan H, Klevernic I, Arthur JS, Alessi DR, Cohen P. Bain J, et al. Among authors: arthur js. Biochem J. 2007 Dec 15;408(3):297-315. doi: 10.1042/BJ20070797. Biochem J. 2007. PMID: 17850214 Free PMC article.
Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth.
Sapkota GP, Kieloch A, Lizcano JM, Lain S, Arthur JS, Williams MR, Morrice N, Deak M, Alessi DR. Sapkota GP, et al. Among authors: arthur js. J Biol Chem. 2001 Jun 1;276(22):19469-82. doi: 10.1074/jbc.M009953200. Epub 2001 Jan 31. J Biol Chem. 2001. PMID: 11297520 Free article.
MSK1 activity is controlled by multiple phosphorylation sites.
McCoy CE, Campbell DG, Deak M, Bloomberg GB, Arthur JS. McCoy CE, et al. Among authors: arthur js. Biochem J. 2005 Apr 15;387(Pt 2):507-17. doi: 10.1042/BJ20041501. Biochem J. 2005. PMID: 15568999 Free PMC article.
175 results