Jin C - Search Results

1

Synthesis and identification of novel 11beta-aryl-4',5'-dihydrospiro[estra-4,9-diene-17beta,4'-oxazole] analogs with dissociated antiprogesterone activities.

Jin C, Manikumar G, Kepler JA, Cook CE, Allan GF, Kiddoe M, Bhattacharjee S, Linton O, Lundeen SG, Sui Z. Jin C, et al. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5754-7. doi: 10.1016/j.bmcl.2007.08.064. Epub 2007 Aug 29. Bioorg Med Chem Lett. 2007. PMID: 17855092

2

Copper-catalyzed cyclization of steroidal acylaminoacetylenes: syntheses of novel 11beta-aryl-17,17- spiro[(4'H,5'-methylene)oxazol]-substituted steroids.

Jin C, Burgess JP, Kepler JA, Cook CE. Jin C, et al. Org Lett. 2007 May 10;9(10):1887-90. doi: 10.1021/ol070447d. Epub 2007 Apr 17. Org Lett. 2007. PMID: 17439133

3

Design, synthesis, and estrogenic activity of a novel estrogen receptor modulator--a hybrid structure of 17beta-estradiol and vitamin E in hippocampal neurons.

Zhao L, Jin C, Mao Z, Gopinathan MB, Rehder K, Brinton RD. Zhao L, et al. Among authors: jin c. J Med Chem. 2007 Sep 6;50(18):4471-81. doi: 10.1021/jm070546x. Epub 2007 Aug 14. J Med Chem. 2007. PMID: 17696335

4

Synthesis and receptor binding properties of 2beta-alkynyl and 2beta-(1,2,3-triazol)substituted 3beta-(substituted phenyl)tropane derivatives.

Jin C, Navarro HA, Carroll FI. Jin C, et al. Bioorg Med Chem. 2008 May 15;16(10):5529-35. doi: 10.1016/j.bmc.2008.04.008. Epub 2008 Apr 10. Bioorg Med Chem. 2008. PMID: 18434164 Free PMC article.

5

Synthesis and monoamine transporter binding properties of 2beta-[3'-(substituted benzyl)isoxazol-5-yl]- and 2beta-[3'-methyl-4'-(substituted phenyl)isoxazol-5-yl]-3beta-(substituted phenyl)tropanes.

Jin C, Navarro HA, Page K, Carroll FI. Jin C, et al. Bioorg Med Chem. 2008 Jul 15;16(14):6682-8. doi: 10.1016/j.bmc.2008.05.073. Epub 2008 Jun 2. Bioorg Med Chem. 2008. PMID: 18556210 Free PMC article.

6

Development of 3-phenyltropane analogues with high affinity for the dopamine and serotonin transporters and low affinity for the norepinephrine transporter.

Jin C, Navarro HA, Carroll FI. Jin C, et al. J Med Chem. 2008 Dec 25;51(24):8048-56. doi: 10.1021/jm801162z. J Med Chem. 2008. PMID: 19053748 Free PMC article.

7

Synthesis and structure-activity relationship of 3beta-(4-alkylthio, -methylsulfinyl, and -methylsulfonylphenyl)tropane and 3beta-(4-alkylthiophenyl)nortropane derivatives for monoamine transporters.

Jin C, Navarro HA, Ivy Carroll F. Jin C, et al. Bioorg Med Chem. 2009 Jul 15;17(14):5126-32. doi: 10.1016/j.bmc.2009.05.052. Epub 2009 May 29. Bioorg Med Chem. 2009. PMID: 19523837 Free PMC article.

8

Synthesis and antihormonal properties of novel 11β-benzoxazole-substituted steroids.

Jin C, Fix SE, Kepler JA, Cook CE. Jin C, et al. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1705-8. doi: 10.1016/j.bmcl.2011.12.110. Epub 2011 Dec 30. Bioorg Med Chem Lett. 2012. PMID: 22260770

9

Discovery of N-{4-[(3-hydroxyphenyl)-3-methylpiperazin-1-yl]methyl-2-methylpropyl}-4-phenoxybenzamide analogues as selective kappa opioid receptor antagonists.

Kormos CM, Jin C, Cueva JP, Runyon SP, Thomas JB, Brieaddy LE, Mascarella SW, Navarro HA, Gilmour BP, Carroll FI. Kormos CM, et al. Among authors: jin c. J Med Chem. 2013 Jun 13;56(11):4551-67. doi: 10.1021/jm400275h. Epub 2013 May 16. J Med Chem. 2013. PMID: 23651437 Free PMC article.

10

Design, synthesis and pharmacological evaluation of 4-hydroxyphenylglycine and 4-hydroxyphenylglycinol derivatives as GPR88 agonists.

Jin C, Decker AM, Langston TL. Jin C, et al. Bioorg Med Chem. 2017 Jan 15;25(2):805-812. doi: 10.1016/j.bmc.2016.11.058. Epub 2016 Dec 1. Bioorg Med Chem. 2017. PMID: 27956039 Free PMC article.

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