Manikumar G - Search Results

1

Synthesis and identification of novel 11beta-aryl-4',5'-dihydrospiro[estra-4,9-diene-17beta,4'-oxazole] analogs with dissociated antiprogesterone activities.

Jin C, Manikumar G, Kepler JA, Cook CE, Allan GF, Kiddoe M, Bhattacharjee S, Linton O, Lundeen SG, Sui Z. Jin C, et al. Among authors: manikumar g. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5754-7. doi: 10.1016/j.bmcl.2007.08.064. Epub 2007 Aug 29. Bioorg Med Chem Lett. 2007. PMID: 17855092

2

Camptothecin analogs with bulky, hydrophobic substituents at the 7-position via a Grignard reaction.

Manikumar G, Wadkins RM, Bearss D, Von Hoff DD, Wani MC, Wall ME. Manikumar G, et al. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5377-81. doi: 10.1016/j.bmcl.2004.08.010. Bioorg Med Chem Lett. 2004. PMID: 15454230

3

Plant antitumor agents. 30. Synthesis and structure activity of novel camptothecin analogs.

Wall ME, Wani MC, Nicholas AW, Manikumar G, Tele C, Moore L, Truesdale A, Leitner P, Besterman JM. Wall ME, et al. Among authors: manikumar g. J Med Chem. 1993 Sep 3;36(18):2689-700. doi: 10.1021/jm00070a013. J Med Chem. 1993. PMID: 8410981

4

Plant antitumor agents. 29. Synthesis and biological activity of ring D and ring E modified analogues of camptothecin.

Nicholas AW, Wani MC, Manikumar G, Wall ME, Kohn KW, Pommier Y. Nicholas AW, et al. Among authors: manikumar g. J Med Chem. 1990 Mar;33(3):972-8. doi: 10.1021/jm00165a014. J Med Chem. 1990. PMID: 2155323

5

Plant antitumor agents. 25. Total synthesis and antileukemic activity of ring A substituted camptothecin analogues. Structure-activity correlations.

Wani MC, Nicholas AW, Manikumar G, Wall ME. Wani MC, et al. Among authors: manikumar g. J Med Chem. 1987 Oct;30(10):1774-9. doi: 10.1021/jm00393a016. J Med Chem. 1987. PMID: 3656353

6

Cationic antiprotozoal drugs. Trypanocidal activity of 2-(4'-formylphenyl)imidazo[1,2-a]pyridinium guanylhydrazones and related derivatives of quaternary heteroaromatic compounds.

Sundberg RJ, Dahlhausen DJ, Manikumar G, Mavunkel B, Biswas A, Srinivasan V, Musallam HA, Reid WA Jr, Ager AL. Sundberg RJ, et al. Among authors: manikumar g. J Med Chem. 1990 Jan;33(1):298-307. doi: 10.1021/jm00163a049. J Med Chem. 1990. PMID: 2296025

7

Plant antimutagenic agents, 2. Flavonoids.

Wall ME, Wani MC, Manikumar G, Abraham P, Taylor H, Hughes TJ, Warner J, McGivney R. Wall ME, et al. Among authors: manikumar g. J Nat Prod. 1988 Nov-Dec;51(6):1084-91. doi: 10.1021/np50060a006. J Nat Prod. 1988. PMID: 3069957

8

Pre-clinical evaluation of SN-38 and novel camptothecin analogs against human chronic B-cell lymphocytic leukemia lymphocytes.

Cohen DP, Adams DJ, Flowers JL, Wall ME, Wani MC, Manikumar G, Colvin OM, Silber R. Cohen DP, et al. Among authors: manikumar g. Leuk Res. 1999 Nov;23(11):1061-70. doi: 10.1016/s0145-2126(99)00133-2. Leuk Res. 1999. PMID: 10576512

9

Topoisomerase I-DNA complex stability induced by camptothecins and its role in drug activity.

Wadkins RM, Bearss D, Manikumar G, Wani MC, Wall ME, Von Hoff DD. Wadkins RM, et al. Among authors: manikumar g. Curr Med Chem Anticancer Agents. 2004 Jul;4(4):327-34. doi: 10.2174/1568011043352894. Curr Med Chem Anticancer Agents. 2004. PMID: 15281905

10

Hydrophilic camptothecin analogs that form extremely stable cleavable complexes with DNA and topoisomerase I.

Wadkins RM, Bearss D, Manikumar G, Wani MC, Wall ME, Von Hoff DD. Wadkins RM, et al. Among authors: manikumar g. Cancer Res. 2004 Sep 15;64(18):6679-83. doi: 10.1158/0008-5472.CAN-04-1885. Cancer Res. 2004. PMID: 15374984

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