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Characterization of a novel phosphodiesterase type 5 inhibitor: JNJ-10258859.
Qiu Y, Bhattacharjee S, Kraft P, John TM, Craig E, Haynes-Johnson D, Guan J, Jiang W, Macielag M, Sui Z, Clancy J, Lundeen S. Qiu Y, et al. Among authors: sui z. Eur J Pharmacol. 2003 Jul 4;472(1-2):73-80. doi: 10.1016/s0014-2999(03)01868-5. Eur J Pharmacol. 2003. PMID: 12860475
Pyrroloquinolone PDE5 inhibitors with improved pharmaceutical profiles for clinical studies on erectile dysfunction.
Jiang W, Guan J, Macielag MJ, Zhang S, Qiu Y, Kraft P, Bhattacharjee S, John TM, Haynes-Johnson D, Lundeen S, Sui Z. Jiang W, et al. Among authors: sui z. J Med Chem. 2005 Mar 24;48(6):2126-33. doi: 10.1021/jm0401098. J Med Chem. 2005. PMID: 15771456
We previously reported a series of potent and selective pyrimidinyl pyrroloquinolone PDE5 inhibitors such as 2a for potential use in male erectile dysfunction (MED) (Sui, Z.; Guan, J.; Macielag, M. J.; Jiang, W.; Zhang, S.; Qiu, Y.; Kraft, P., Bhattacharjee, S.; Joh …
We previously reported a series of potent and selective pyrimidinyl pyrroloquinolone PDE5 inhibitors such as 2a for potential use in male er …
675 results