Sansregret L - Search Results

1

Increased expression and activity of nuclear cathepsin L in cancer cells suggests a novel mechanism of cell transformation.

Goulet B, Sansregret L, Leduy L, Bogyo M, Weber E, Chauhan SS, Nepveu A. Goulet B, et al. Among authors: sansregret l. Mol Cancer Res. 2007 Sep;5(9):899-907. doi: 10.1158/1541-7786.MCR-07-0160. Mol Cancer Res. 2007. PMID: 17855659

2

A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor.

Goulet B, Baruch A, Moon NS, Poirier M, Sansregret LL, Erickson A, Bogyo M, Nepveu A. Goulet B, et al. Among authors: sansregret ll. Mol Cell. 2004 Apr 23;14(2):207-19. doi: 10.1016/s1097-2765(04)00209-6. Mol Cell. 2004. PMID: 15099520 Free article.

3

The p110 isoform of the CDP/Cux transcription factor accelerates entry into S phase.

Sansregret L, Goulet B, Harada R, Wilson B, Leduy L, Bertoglio J, Nepveu A. Sansregret L, et al. Mol Cell Biol. 2006 Mar;26(6):2441-55. doi: 10.1128/MCB.26.6.2441-2455.2006. Mol Cell Biol. 2006. PMID: 16508018 Free PMC article.

4

Genome-wide location analysis and expression studies reveal a role for p110 CUX1 in the activation of DNA replication genes.

Harada R, Vadnais C, Sansregret L, Leduy L, Bérubé G, Robert F, Nepveu A. Harada R, et al. Among authors: sansregret l. Nucleic Acids Res. 2008 Jan;36(1):189-202. doi: 10.1093/nar/gkm970. Epub 2007 Nov 14. Nucleic Acids Res. 2008. PMID: 18003658 Free PMC article.

5

The multiple roles of CUX1: insights from mouse models and cell-based assays.

Sansregret L, Nepveu A. Sansregret L, et al. Gene. 2008 Apr 15;412(1-2):84-94. doi: 10.1016/j.gene.2008.01.017. Epub 2008 Feb 2. Gene. 2008. PMID: 18313863 Review.

6

Hyperphosphorylation by cyclin B/CDK1 in mitosis resets CUX1 DNA binding clock at each cell cycle.

Sansregret L, Gallo D, Santaguida M, Leduy L, Harada R, Nepveu A. Sansregret L, et al. J Biol Chem. 2010 Oct 22;285(43):32834-32843. doi: 10.1074/jbc.M110.156406. Epub 2010 Aug 19. J Biol Chem. 2010. PMID: 20729212 Free PMC article.

7

p110 CUX1 homeodomain protein stimulates cell migration and invasion in part through a regulatory cascade culminating in the repression of E-cadherin and occludin.

Kedinger V, Sansregret L, Harada R, Vadnais C, Cadieux C, Fathers K, Park M, Nepveu A. Kedinger V, et al. Among authors: sansregret l. J Biol Chem. 2009 Oct 2;284(40):27701-11. doi: 10.1074/jbc.M109.031849. Epub 2009 Jul 27. J Biol Chem. 2009. PMID: 19635798 Free PMC article.

8

Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure.

Sansregret L, Vadnais C, Livingstone J, Kwiatkowski N, Awan A, Cadieux C, Leduy L, Hallett MT, Nepveu A. Sansregret L, et al. Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):1949-54. doi: 10.1073/pnas.1008403108. Epub 2011 Jan 18. Proc Natl Acad Sci U S A. 2011. PMID: 21245318 Free PMC article.

9

Gene signatures of genomic instability as prognostic tools for breast cancer.

Sansregret L, Nepveu A. Sansregret L, et al. Future Oncol. 2011 May;7(5):591-4. doi: 10.2217/fon.11.34. Future Oncol. 2011. PMID: 21568672 No abstract available.

10

Determinants and clinical implications of chromosomal instability in cancer.

Sansregret L, Vanhaesebroeck B, Swanton C. Sansregret L, et al. Nat Rev Clin Oncol. 2018 Mar;15(3):139-150. doi: 10.1038/nrclinonc.2017.198. Epub 2018 Jan 3. Nat Rev Clin Oncol. 2018. PMID: 29297505 Review.

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