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Bexarotene induces dyslipidemia by increased very low-density lipoprotein production and cholesteryl ester transfer protein-mediated reduction of high-density lipoprotein.
de Vries-van der Weij J, de Haan W, Hu L, Kuif M, Oei HL, van der Hoorn JW, Havekes LM, Princen HM, Romijn JA, Smit JW, Rensen PC. de Vries-van der Weij J, et al. Among authors: romijn ja. Endocrinology. 2009 May;150(5):2368-75. doi: 10.1210/en.2008-1540. Epub 2009 Jan 15. Endocrinology. 2009. PMID: 19147676 Clinical Trial.
PXR agonism decreases plasma HDL levels in ApoE3-Leiden.CETP mice.
de Haan W, de Vries-van der Weij J, Mol IM, Hoekstra M, Romijn JA, Jukema JW, Havekes LM, Princen HM, Rensen PC. de Haan W, et al. Among authors: romijn ja. Biochim Biophys Acta. 2009 Mar;1791(3):191-7. doi: 10.1016/j.bbalip.2008.12.008. Epub 2008 Dec 25. Biochim Biophys Acta. 2009. PMID: 19150509
Ritonavir protects against the development of atherosclerosis in APOE*3-Leiden mice.
den Boer MA, Westerterp M, de Vries-van der Weij J, Wang Y, Hu L, Espirito Santo SM, Kooistra T, Reiss P, Romijn JA, Havekes LM, Rensen PC. den Boer MA, et al. Among authors: romijn ja. Atherosclerosis. 2010 Jun;210(2):381-7. doi: 10.1016/j.atherosclerosis.2009.11.043. Epub 2009 Dec 1. Atherosclerosis. 2010. PMID: 20060117
602 results