Koumenis C - Search Results

1

Identification and biological evaluation of a novel and potent small molecule radiation sensitizer via an unbiased screen of a chemical library.

Lally BE, Geiger GA, Kridel S, Arcury-Quandt AE, Robbins ME, Kock ND, Wheeler K, Peddi P, Georgakilas A, Kao GD, Koumenis C. Lally BE, et al. Among authors: koumenis c. Cancer Res. 2007 Sep 15;67(18):8791-9. doi: 10.1158/0008-5472.CAN-07-0477. Cancer Res. 2007. PMID: 17875720 Free PMC article.

2

Attenuated response of p53 and p21 in primary cultures of human prostatic epithelial cells exposed to DNA-damaging agents.

Girinsky T, Koumenis C, Graeber TG, Peehl DM, Giaccia AJ. Girinsky T, et al. Among authors: koumenis c. Cancer Res. 1995 Sep 1;55(17):3726-31. Cancer Res. 1995. PMID: 7543816

3

Hypoxia induces p53 accumulation through MDM2 down-regulation and inhibition of E6-mediated degradation.

Alarcón R, Koumenis C, Geyer RK, Maki CG, Giaccia AJ. Alarcón R, et al. Among authors: koumenis c. Cancer Res. 1999 Dec 15;59(24):6046-51. Cancer Res. 1999. PMID: 10626788

4

p53 promotes selection for Fas-mediated apoptotic resistance.

Maecker HL, Koumenis C, Giaccia AJ. Maecker HL, et al. Among authors: koumenis c. Cancer Res. 2000 Aug 15;60(16):4638-44. Cancer Res. 2000. PMID: 10969818

5

1alpha,25-dihydroxyvitamin D(3) (calcitriol) and its analogue, 19-nor-1alpha,25(OH)(2)D(2), potentiate the effects of ionising radiation on human prostate cancer cells.

Dunlap N, Schwartz GG, Eads D, Cramer SD, Sherk AB, John V, Koumenis C. Dunlap N, et al. Among authors: koumenis c. Br J Cancer. 2003 Aug 18;89(4):746-53. doi: 10.1038/sj.bjc.6601161. Br J Cancer. 2003. PMID: 12915889 Free PMC article.

6

Vitamin D receptor and p21/WAF1 are targets of genistein and 1,25-dihydroxyvitamin D3 in human prostate cancer cells.

Rao A, Coan A, Welsh JE, Barclay WW, Koumenis C, Cramer SD. Rao A, et al. Among authors: koumenis c. Cancer Res. 2004 Mar 15;64(6):2143-7. doi: 10.1158/0008-5472.can-03-3480. Cancer Res. 2004. PMID: 15026355

7

Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells.

Little JL, Wheeler FB, Fels DR, Koumenis C, Kridel SJ. Little JL, et al. Among authors: koumenis c. Cancer Res. 2007 Feb 1;67(3):1262-9. doi: 10.1158/0008-5472.CAN-06-1794. Cancer Res. 2007. PMID: 17283163

8

Preferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways.

Fels DR, Ye J, Segan AT, Kridel SJ, Spiotto M, Olson M, Koong AC, Koumenis C. Fels DR, et al. Among authors: koumenis c. Cancer Res. 2008 Nov 15;68(22):9323-30. doi: 10.1158/0008-5472.CAN-08-2873. Cancer Res. 2008. PMID: 19010906 Free PMC article.

9

Disruption of crosstalk between the fatty acid synthesis and proteasome pathways enhances unfolded protein response signaling and cell death.

Little JL, Wheeler FB, Koumenis C, Kridel SJ. Little JL, et al. Among authors: koumenis c. Mol Cancer Ther. 2008 Dec;7(12):3816-24. doi: 10.1158/1535-7163.MCT-08-0558. Mol Cancer Ther. 2008. PMID: 19074856 Free PMC article.

10

In vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection.

Marotta D, Karar J, Jenkins WT, Kumanova M, Jenkins KW, Tobias JW, Baldwin D, Hatzigeorgiou A, Alexiou P, Evans SM, Alarcon R, Maity A, Koch C, Koumenis C. Marotta D, et al. Among authors: koumenis c. Cancer Res. 2011 Feb 1;71(3):779-89. doi: 10.1158/0008-5472.CAN-10-3061. Epub 2011 Jan 25. Cancer Res. 2011. PMID: 21266355 Free PMC article.

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