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Blockade of protein geranylgeranylation inhibits Cdk2-dependent p27Kip1 phosphorylation on Thr187 and accumulates p27Kip1 in the nucleus: implications for breast cancer therapy.
Kazi A, Carie A, Blaskovich MA, Bucher C, Thai V, Moulder S, Peng H, Carrico D, Pusateri E, Pledger WJ, Berndt N, Hamilton A, Sebti SM. Kazi A, et al. Among authors: sebti sm. Mol Cell Biol. 2009 Apr;29(8):2254-63. doi: 10.1128/MCB.01029-08. Epub 2009 Feb 9. Mol Cell Biol. 2009. PMID: 19204084 Free PMC article.
Targeting protein prenylation for cancer therapy.
Berndt N, Hamilton AD, Sebti SM. Berndt N, et al. Among authors: sebti sm. Nat Rev Cancer. 2011 Oct 24;11(11):775-91. doi: 10.1038/nrc3151. Nat Rev Cancer. 2011. PMID: 22020205 Free PMC article.
293 results