Holder DJ - Search Results

1

Diagnosis of drug-induced renal tubular toxicity using global gene expression profiles.

Jiang Y, Gerhold DL, Holder DJ, Figueroa DJ, Bailey WJ, Guan P, Skopek TR, Sistare FD, Sina JF. Jiang Y, et al. Among authors: holder dj. J Transl Med. 2007 Oct 1;5:47. doi: 10.1186/1479-5876-5-47. J Transl Med. 2007. PMID: 17908307 Free PMC article.

2

Universal Toxicity Gene Signatures for Early Identification of Drug-Induced Tissue Injuries in Rats.

Glaab WE, Holder D, He YD, Bailey WJ, Gerhold DL, Beare C, Erdos Z, Lane P, Michna L, Muniappa N, Lawrence JW, Tanis KQ, Sina JF, Skopek TR, Sistare FD. Glaab WE, et al. Toxicol Sci. 2021 May 27;181(2):148-159. doi: 10.1093/toxsci/kfab038. Toxicol Sci. 2021. PMID: 33837425

3

A performance evaluation of three drug-induced liver injury biomarkers in the rat: alpha-glutathione S-transferase, arginase 1, and 4-hydroxyphenyl-pyruvate dioxygenase.

Bailey WJ, Holder D, Patel H, Devlin P, Gonzalez RJ, Hamilton V, Muniappa N, Hamlin DM, Thomas CE, Sistare FD, Glaab WE. Bailey WJ, et al. Toxicol Sci. 2012 Dec;130(2):229-44. doi: 10.1093/toxsci/kfs243. Epub 2012 Aug 7. Toxicol Sci. 2012. PMID: 22872058

4

Urinary biomarkers trefoil factor 3 and albumin enable early detection of kidney tubular injury.

Yu Y, Jin H, Holder D, Ozer JS, Villarreal S, Shughrue P, Shi S, Figueroa DJ, Clouse H, Su M, Muniappa N, Troth SP, Bailey W, Seng J, Aslamkhan AG, Thudium D, Sistare FD, Gerhold DL. Yu Y, et al. Among authors: holder d. Nat Biotechnol. 2010 May;28(5):470-7. doi: 10.1038/nbt.1624. Nat Biotechnol. 2010. PMID: 20458317

5

A panel of urinary biomarkers to monitor reversibility of renal injury and a serum marker with improved potential to assess renal function.

Ozer JS, Dieterle F, Troth S, Perentes E, Cordier A, Verdes P, Staedtler F, Mahl A, Grenet O, Roth DR, Wahl D, Legay F, Holder D, Erdos Z, Vlasakova K, Jin H, Yu Y, Muniappa N, Forest T, Clouse HK, Reynolds S, Bailey WJ, Thudium DT, Topper MJ, Skopek TR, Sina JF, Glaab WE, Vonderscher J, Maurer G, Chibout SD, Sistare FD, Gerhold DL. Ozer JS, et al. Nat Biotechnol. 2010 May;28(5):486-94. doi: 10.1038/nbt.1627. Nat Biotechnol. 2010. PMID: 20458319

6

Evaluation of the relative performance of 12 urinary biomarkers for renal safety across 22 rat sensitivity and specificity studies.

Vlasakova K, Erdos Z, Troth SP, McNulty K, Chapeau-Campredon V, Mokrzycki N, Muniappa N, Gu YZ, Holder D, Bailey WJ, Sistare FD, Glaab WE. Vlasakova K, et al. Toxicol Sci. 2014 Mar;138(1):3-20. doi: 10.1093/toxsci/kft330. Epub 2013 Dec 21. Toxicol Sci. 2014. PMID: 24361871

7

Chronic neuropathic pain is accompanied by global changes in gene expression and shares pathobiology with neurodegenerative diseases.

Wang H, Sun H, Della Penna K, Benz RJ, Xu J, Gerhold DL, Holder DJ, Koblan KS. Wang H, et al. Among authors: holder dj. Neuroscience. 2002;114(3):529-46. doi: 10.1016/s0306-4522(02)00341-x. Neuroscience. 2002. PMID: 12220557

8

Towards consensus practices to qualify safety biomarkers for use in early drug development.

Sistare FD, Dieterle F, Troth S, Holder DJ, Gerhold D, Andrews-Cleavenger D, Baer W, Betton G, Bounous D, Carl K, Collins N, Goering P, Goodsaid F, Gu YZ, Guilpin V, Harpur E, Hassan A, Jacobson-Kram D, Kasper P, Laurie D, Lima BS, Maciulaitis R, Mattes W, Maurer G, Obert LA, Ozer J, Papaluca-Amati M, Phillips JA, Pinches M, Schipper MJ, Thompson KL, Vamvakas S, Vidal JM, Vonderscher J, Walker E, Webb C, Yu Y. Sistare FD, et al. Among authors: holder dj. Nat Biotechnol. 2010 May;28(5):446-54. doi: 10.1038/nbt.1634. Epub 2010 May 10. Nat Biotechnol. 2010. PMID: 20458314

9

Androgens drive divergent responses to salt stress in male versus female rat kidneys.

Gerhold D, Bagchi A, Lu M, Figueroa D, Keenan K, Holder D, Wang Y, Jin H, Connolly B, Austin C, Alonso-Galicia M. Gerhold D, et al. Genomics. 2007 Jun;89(6):731-44. doi: 10.1016/j.ygeno.2007.01.009. Epub 2007 May 4. Genomics. 2007. PMID: 17481853 Free article.

10

Dorsal horn-enriched genes identified by DNA microarray, in situ hybridization and immunohistochemistry.

Sun H, Xu J, Della Penna KB, Benz RJ, Kinose F, Holder DJ, Koblan KS, Gerhold DL, Wang H. Sun H, et al. Among authors: holder dj. BMC Neurosci. 2002 Aug 20;3:11. doi: 10.1186/1471-2202-3-11. BMC Neurosci. 2002. PMID: 12188929 Free PMC article.

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