Hasty P - Search Results

1

Cisplatin depletes TREX2 and causes Robertsonian translocations as seen in TREX2 knockout cells.

Chen MJ, Dumitrache LC, Wangsa D, Ma SM, Padilla-Nash H, Ried T, Hasty P. Chen MJ, et al. Among authors: hasty p. Cancer Res. 2007 Oct 1;67(19):9077-83. doi: 10.1158/0008-5472.CAN-07-1146. Cancer Res. 2007. PMID: 17909011

2

A genotoxic screen: rapid analysis of cellular dose-response to a wide range of agents that either damage DNA or alter genome maintenance pathways.

Marple T, Li H, Hasty P. Marple T, et al. Among authors: hasty p. Mutat Res. 2004 Oct 4;554(1-2):253-66. doi: 10.1016/j.mrfmmm.2004.05.004. Mutat Res. 2004. PMID: 15450423

3

Embryonic stem cells deficient for Brca2 or Blm exhibit divergent genotoxic profiles that support opposing activities during homologous recombination.

Marple T, Kim TM, Hasty P. Marple T, et al. Among authors: hasty p. Mutat Res. 2006 Dec 1;602(1-2):110-20. doi: 10.1016/j.mrfmmm.2006.08.005. Epub 2006 Sep 25. Mutat Res. 2006. PMID: 16997331

4

Biochemical and cellular characteristics of the 3' -> 5' exonuclease TREX2.

Chen MJ, Ma SM, Dumitrache LC, Hasty P. Chen MJ, et al. Among authors: hasty p. Nucleic Acids Res. 2007;35(8):2682-94. doi: 10.1093/nar/gkm151. Epub 2007 Apr 10. Nucleic Acids Res. 2007. PMID: 17426129 Free PMC article.

5

HPRT minigene generates chimeric transcripts as a by-product of gene targeting.

Holcomb VB, Kim TM, Dumitrache LC, Ma SM, Chen MJ, Hasty P. Holcomb VB, et al. Among authors: hasty p. Genesis. 2007 May;45(5):275-81. doi: 10.1002/dvg.20300. Genesis. 2007. PMID: 17457929

6

Ku80 deletion suppresses spontaneous tumors and induces a p53-mediated DNA damage response.

Holcomb VB, Rodier F, Choi Y, Busuttil RA, Vogel H, Vijg J, Campisi J, Hasty P. Holcomb VB, et al. Among authors: hasty p. Cancer Res. 2008 Nov 15;68(22):9497-502. doi: 10.1158/0008-5472.CAN-08-2085. Cancer Res. 2008. PMID: 19010925 Free PMC article.

7

TREX2 exonuclease defective cells exhibit double-strand breaks and chromosomal fragments but not Robertsonian translocations.

Dumitrache LC, Hu L, Hasty P. Dumitrache LC, et al. Among authors: hasty p. Mutat Res. 2009 Mar 9;662(1-2):84-7. doi: 10.1016/j.mrfmmm.2008.11.012. Epub 2008 Nov 27. Mutat Res. 2009. PMID: 19094998 Free PMC article.

8

The phenotype of FancB-mutant mouse embryonic stem cells.

Kim TM, Ko JH, Choi YJ, Hu L, Hasty P. Kim TM, et al. Among authors: hasty p. Mutat Res. 2011 Jul 1;712(1-2):20-7. doi: 10.1016/j.mrfmmm.2011.03.010. Epub 2011 Mar 30. Mutat Res. 2011. PMID: 21458466 Free PMC article.

9

Trex2 enables spontaneous sister chromatid exchanges without facilitating DNA double-strand break repair.

Dumitrache LC, Hu L, Son MY, Li H, Wesevich A, Scully R, Stark J, Hasty P. Dumitrache LC, et al. Among authors: hasty p. Genetics. 2011 Aug;188(4):787-97. doi: 10.1534/genetics.111.129833. Epub 2011 May 5. Genetics. 2011. PMID: 21546543 Free PMC article.

10

Two replication fork maintenance pathways fuse inverted repeats to rearrange chromosomes.

Hu L, Kim TM, Son MY, Kim SA, Holland CL, Tateishi S, Kim DH, Yew PR, Montagna C, Dumitrache LC, Hasty P. Hu L, et al. Among authors: hasty p. Nature. 2013 Sep 26;501(7468):569-72. doi: 10.1038/nature12500. Epub 2013 Sep 8. Nature. 2013. PMID: 24013173 Free PMC article.

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