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Small molecule inhibitors of integrin alpha2beta1.
Choi S, Vilaire G, Marcinkiewicz C, Winkler JD, Bennett JS, DeGrado WF. Choi S, et al. Among authors: winkler jd. J Med Chem. 2007 Nov 1;50(22):5457-62. doi: 10.1021/jm070252b. Epub 2007 Oct 4. J Med Chem. 2007. PMID: 17915848 Free PMC article.
Nontoxic membrane-active antimicrobial arylamide oligomers.
Liu D, Choi S, Chen B, Doerksen RJ, Clements DJ, Winkler JD, Klein ML, DeGrado WF. Liu D, et al. Among authors: winkler jd. Angew Chem Int Ed Engl. 2004 Feb 20;43(9):1158-62. doi: 10.1002/anie.200352791. Angew Chem Int Ed Engl. 2004. PMID: 14983462 No abstract available.
The design and evaluation of heparin-binding foldamers.
Choi S, Clements DJ, Pophristic V, Ivanov I, Vemparala S, Bennett JS, Klein ML, Winkler JD, DeGrado WF. Choi S, et al. Among authors: winkler jd. Angew Chem Int Ed Engl. 2005 Oct 21;44(41):6685-9. doi: 10.1002/anie.200501279. Angew Chem Int Ed Engl. 2005. PMID: 16094685 No abstract available.
Crystal structures of AKR1C3 containing an N-(aryl)amino-benzoate inhibitor and a bifunctional AKR1C3 inhibitor and androgen receptor antagonist. Therapeutic leads for castrate resistant prostate cancer.
Chen M, Adeniji AO, Twenter BM, Winkler JD, Christianson DW, Penning TM. Chen M, et al. Among authors: winkler jd. Bioorg Med Chem Lett. 2012 May 15;22(10):3492-7. doi: 10.1016/j.bmcl.2012.03.085. Epub 2012 Mar 29. Bioorg Med Chem Lett. 2012. PMID: 22507964 Free PMC article.
Identification of a novel family of BRAF(V600E) inhibitors.
Qin J, Xie P, Ventocilla C, Zhou G, Vultur A, Chen Q, Liu Q, Herlyn M, Winkler J, Marmorstein R. Qin J, et al. J Med Chem. 2012 Jun 14;55(11):5220-30. doi: 10.1021/jm3004416. Epub 2012 May 18. J Med Chem. 2012. PMID: 22537109 Free PMC article.
169 results