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Cannabidiol negatively modulates adenosine A2A receptor functioning in living cells.
Sánchez-Fernández N, Gómez-Acero L, Sarasola LI, Argerich J, Chevigné A, Jacobson KA, Ciruela F, Fernández-Dueñas V, Aso E. Sánchez-Fernández N, et al. Among authors: chevigne a. Acta Neuropsychiatr. 2024 Oct;36(5):320-324. doi: 10.1017/neu.2023.30. Epub 2023 Aug 22. Acta Neuropsychiatr. 2024. PMID: 37605951
Pharmacological Characterization and Radiolabeling of VUF15485, a High-Affinity Small-Molecule Agonist for the Atypical Chemokine Receptor ACKR3.
Zarca AM, Adlere I, Viciano CP, Arimont-Segura M, Meyrath M, Simon IA, Bebelman JP, Laan D, Custers HGJ, Janssen E, Versteegh KL, Buzink MCML, Nesheva DN, Bosma R, de Esch IJP, Vischer HF, Wijtmans M, Szpakowska M, Chevigné A, Hoffmann C, de Graaf C, Zarzycka BA, Windhorst AD, Smit MJ, Leurs R. Zarca AM, et al. Among authors: chevigne a. Mol Pharmacol. 2024 Mar 14;105(4):301-312. doi: 10.1124/molpharm.123.000835. Mol Pharmacol. 2024. PMID: 38346795
Computationally designed GPCR quaternary structures bias signaling pathway activation.
Paradis JS, Feng X, Murat B, Jefferson RE, Sokrat B, Szpakowska M, Hogue M, Bergkamp ND, Heydenreich FM, Smit MJ, Chevigné A, Bouvier M, Barth P. Paradis JS, et al. Among authors: chevigne a. Nat Commun. 2022 Nov 11;13(1):6826. doi: 10.1038/s41467-022-34382-7. Nat Commun. 2022. PMID: 36369272 Free PMC article.
How Carvedilol activates β2-adrenoceptors.
Benkel T, Zimmermann M, Zeiner J, Bravo S, Merten N, Lim VJY, Matthees ESF, Drube J, Miess-Tanneberg E, Malan D, Szpakowska M, Monteleone S, Grimes J, Koszegi Z, Lanoiselée Y, O'Brien S, Pavlaki N, Dobberstein N, Inoue A, Nikolaev V, Calebiro D, Chevigné A, Sasse P, Schulz S, Hoffmann C, Kolb P, Waldhoer M, Simon K, Gomeza J, Kostenis E. Benkel T, et al. Among authors: chevigne a. Nat Commun. 2022 Nov 19;13(1):7109. doi: 10.1038/s41467-022-34765-w. Nat Commun. 2022. PMID: 36402762 Free PMC article.
84 results