Villa V - Search Results

1

Different structural stability and toxicity of PrP(ARR) and PrP(ARQ) sheep prion protein variants.

Paludi D, Thellung S, Chiovitti K, Corsaro A, Villa V, Russo C, Ianieri A, Bertsch U, Kretzschmar HA, Aceto A, Florio T. Paludi D, et al. Among authors: villa v. J Neurochem. 2007 Dec;103(6):2291-300. doi: 10.1111/j.1471-4159.2007.04934.x. Epub 2007 Oct 4. J Neurochem. 2007. PMID: 17919292 Free article.

2

Contribution of two conserved glycine residues to fibrillogenesis of the 106-126 prion protein fragment. Evidence that a soluble variant of the 106-126 peptide is neurotoxic.

Florio T, Paludi D, Villa V, Principe DR, Corsaro A, Millo E, Damonte G, D'Arrigo C, Russo C, Schettini G, Aceto A. Florio T, et al. Among authors: villa v. J Neurochem. 2003 Apr;85(1):62-72. doi: 10.1046/j.1471-4159.2003.01664.x. J Neurochem. 2003. PMID: 12641727 Free article.

3

Intracellular accumulation of a mild-denatured monomer of the human PrP fragment 90-231, as possible mechanism of its neurotoxic effects.

Chiovitti K, Corsaro A, Thellung S, Villa V, Paludi D, D'Arrigo C, Russo C, Perico A, Ianieri A, Di Cola D, Vergara A, Aceto A, Florio T. Chiovitti K, et al. Among authors: villa v. J Neurochem. 2007 Dec;103(6):2597-609. doi: 10.1111/j.1471-4159.2007.04965.x. Epub 2007 Oct 18. J Neurochem. 2007. PMID: 17944873 Free article.

4

Characterization of the proapoptotic intracellular mechanisms induced by a toxic conformer of the recombinant human prion protein fragment 90-231.

Villa V, Corsaro A, Thellung S, Paludi D, Chiovitti K, Venezia V, Nizzari M, Russo C, Schettini G, Aceto A, Florio T. Villa V, et al. Ann N Y Acad Sci. 2006 Dec;1090:276-91. doi: 10.1196/annals.1378.030. Ann N Y Acad Sci. 2006. PMID: 17384271

5

Amino-terminally truncated prion protein PrP90-231 induces microglial activation in vitro.

Thellung S, Corsaro A, Villa V, Venezia V, Nizzari M, Bisaglia M, Russo C, Schettini G, Aceto A, Florio T. Thellung S, et al. Among authors: villa v. Ann N Y Acad Sci. 2007 Jan;1096:258-70. doi: 10.1196/annals.1397.092. Ann N Y Acad Sci. 2007. PMID: 17405937

6

ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation.

Thellung S, Villa V, Corsaro A, Pellistri F, Venezia V, Russo C, Aceto A, Robello M, Florio T. Thellung S, et al. Among authors: villa v. Glia. 2007 Nov 1;55(14):1469-85. doi: 10.1002/glia.20559. Glia. 2007. PMID: 17705195

7

Dual modulation of ERK1/2 and p38 MAP kinase activities induced by minocycline reverses the neurotoxic effects of the prion protein fragment 90-231.

Corsaro A, Thellung S, Chiovitti K, Villa V, Simi A, Raggi F, Paludi D, Russo C, Aceto A, Florio T. Corsaro A, et al. Among authors: villa v. Neurotox Res. 2009 Feb;15(2):138-54. doi: 10.1007/s12640-009-9015-3. Epub 2009 Feb 26. Neurotox Res. 2009. PMID: 19384577

8

High hydrophobic amino acid exposure is responsible of the neurotoxic effects induced by E200K or D202N disease-related mutations of the human prion protein.

Corsaro A, Thellung S, Bucciarelli T, Scotti L, Chiovitti K, Villa V, D'Arrigo C, Aceto A, Florio T. Corsaro A, et al. Among authors: villa v. Int J Biochem Cell Biol. 2011 Mar;43(3):372-82. doi: 10.1016/j.biocel.2010.11.007. Epub 2010 Nov 19. Int J Biochem Cell Biol. 2011. PMID: 21094273

9

Recombinant human prion protein fragment 90-231, a useful model to study prion neurotoxicity.

Corsaro A, Thellung S, Villa V, Nizzari M, Aceto A, Florio T. Corsaro A, et al. Among authors: villa v. OMICS. 2012 Jan-Feb;16(1-2):50-9. doi: 10.1089/omi.2011.0038. OMICS. 2012. PMID: 22321015

10

Calcium binding promotes prion protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure.

Sorrentino S, Bucciarelli T, Corsaro A, Tosatto A, Thellung S, Villa V, Schininà ME, Maras B, Galeno R, Scotti L, Creati F, Marrone A, Re N, Aceto A, Florio T, Mazzanti M. Sorrentino S, et al. Among authors: villa v. PLoS One. 2012;7(7):e38314. doi: 10.1371/journal.pone.0038314. Epub 2012 Jul 11. PLoS One. 2012. PMID: 22811758 Free PMC article.

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