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Different composition of the human and the mouse gammadelta T cell receptor explains different phenotypes of CD3gamma and CD3delta immunodeficiencies.
Siegers GM, Swamy M, Fernández-Malavé E, Minguet S, Rathmann S, Guardo AC, Pérez-Flores V, Regueiro JR, Alarcón B, Fisch P, Schamel WW. Siegers GM, et al. Among authors: fisch p. J Exp Med. 2007 Oct 29;204(11):2537-44. doi: 10.1084/jem.20070782. Epub 2007 Oct 8. J Exp Med. 2007. PMID: 17923503 Free PMC article.
The CD3 conformational change in the γδ T cell receptor is not triggered by antigens but can be enforced to enhance tumor killing.
Dopfer EP, Hartl FA, Oberg HH, Siegers GM, Yousefi OS, Kock S, Fiala GJ, Garcillán B, Sandstrom A, Alarcón B, Regueiro JR, Kabelitz D, Adams EJ, Minguet S, Wesch D, Fisch P, Schamel WWA. Dopfer EP, et al. Among authors: fisch p. Cell Rep. 2014 Jun 12;7(5):1704-1715. doi: 10.1016/j.celrep.2014.04.049. Epub 2014 May 22. Cell Rep. 2014. PMID: 24857663 Free article.
Stoichiometry and intracellular fate of TRIM-containing TCR complexes.
Swamy M, Siegers GM, Fiala GJ, Molnar E, Dopfer EP, Fisch P, Schraven B, Schamel WW. Swamy M, et al. Among authors: fisch p. Cell Commun Signal. 2010 Mar 18;8:5. doi: 10.1186/1478-811X-8-5. Cell Commun Signal. 2010. PMID: 20298603 Free PMC article.
Enrichment of the rare CD4⁺ γδ T-cell subset in patients with atypical CD3δ deficiency.
Garcillán B, Mazariegos MS, Fisch P, Res PC, Muñoz-Ruiz M, Gil J, López-Granados E, Fernández-Malavé E, Regueiro JR. Garcillán B, et al. Among authors: fisch p. J Allergy Clin Immunol. 2014 Apr;133(4):1205-8. doi: 10.1016/j.jaci.2013.10.002. Epub 2013 Nov 28. J Allergy Clin Immunol. 2014. PMID: 24290291 No abstract available.
148 results