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Page 1
SAR of a series of anti-HSV-1 acridone derivatives, and a rational acridone-based design of a new anti-HSV-1 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridine series.
Bernardino AM, Castro HC, Frugulhetti IC, Loureiro NI, Azevedo AR, Pinheiro LC, Souza TM, Giongo V, Passamani F, Magalhães UO, Albuquerque MG, Cabral LM, Rodrigues CR. Bernardino AM, et al. Among authors: loureiro ni. Bioorg Med Chem. 2008 Jan 1;16(1):313-21. doi: 10.1016/j.bmc.2007.09.032. Epub 2007 Sep 22. Bioorg Med Chem. 2008. PMID: 17937990
HIV-1 reverse transcriptase: a therapeutical target in the spotlight.
Castro HC, Loureiro NI, Pujol-Luz M, Souza AM, Albuquerque MG, Santos DO, Cabral LM, Frugulhetti IC, Rodrigues CR. Castro HC, et al. Among authors: loureiro ni. Curr Med Chem. 2006;13(3):313-24. doi: 10.2174/092986706775476089. Curr Med Chem. 2006. PMID: 16475939 Review.
Looking at the proteases from a simple perspective.
Castro HC, Abreu PA, Geraldo RB, Martins RC, dos Santos R, Loureiro NI, Cabral LM, Rodrigues CR. Castro HC, et al. Among authors: loureiro ni. J Mol Recognit. 2011 Mar-Apr;24(2):165-81. doi: 10.1002/jmr.1091. J Mol Recognit. 2011. PMID: 21360607 Review.
Ecotin modulates thrombin activity through exosite-2 interactions.
Castro HC, Monteiro RQ, Assafim M, Loureiro NI, Craik C, Zingali RB. Castro HC, et al. Among authors: loureiro ni. Int J Biochem Cell Biol. 2006;38(11):1893-900. doi: 10.1016/j.biocel.2006.05.001. Epub 2006 May 17. Int J Biochem Cell Biol. 2006. PMID: 16843700
Design, synthesis, SAR, and biological evaluation of new 4-(phenylamino)thieno[2,3-b]pyridine derivatives.
Bernardino AM, da Silva Pinheiro LC, Rodrigues CR, Loureiro NI, Castro HC, Lanfredi-Rangel A, Sabatini-Lopes J, Borges JC, Carvalho JM, Romeiro GA, Ferreira VF, Frugulhetti IC, Vannier-Santos MA. Bernardino AM, et al. Among authors: loureiro ni. Bioorg Med Chem. 2006 Aug 15;14(16):5765-70. doi: 10.1016/j.bmc.2006.03.013. Epub 2006 Jun 14. Bioorg Med Chem. 2006. PMID: 16781157