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Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases.
Lahm A, Paolini C, Pallaoro M, Nardi MC, Jones P, Neddermann P, Sambucini S, Bottomley MJ, Lo Surdo P, Carfí A, Koch U, De Francesco R, Steinkühler C, Gallinari P. Lahm A, et al. Among authors: bottomley mj. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17335-40. doi: 10.1073/pnas.0706487104. Epub 2007 Oct 23. Proc Natl Acad Sci U S A. 2007. PMID: 17956988 Free PMC article.
Bactericidal human monoclonal antibody 1B1 shows specificity for meningococcal factor H binding protein variant 2 and displaces human factor H.
Veggi D, Chesterman CC, Santini L, Huang Y, Pacchiani N, Sierra J, Chen L, Laliberte J, Bianchi F, Cozzi R, Frigimelica E, Maione D, Finco O, Bottomley MJ. Veggi D, et al. Among authors: bottomley mj. FASEB Bioadv. 2024 Jun 27;6(8):235-248. doi: 10.1096/fba.2023-00077. eCollection 2024 Aug. FASEB Bioadv. 2024. PMID: 39114449 Free PMC article.
Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity.
Williams JA, Biancucci M, Lessen L, Tian S, Balsaraf A, Chen L, Chesterman C, Maruggi G, Vandepaer S, Huang Y, Mallett CP, Steff AM, Bottomley MJ, Malito E, Wahome N, Harshbarger WD. Williams JA, et al. Among authors: bottomley mj. Sci Adv. 2023 Jun 9;9(23):eadg0330. doi: 10.1126/sciadv.adg0330. Epub 2023 Jun 7. Sci Adv. 2023. PMID: 37285422 Free PMC article.
Endocytosis: How dynamin sets vesicles PHree!
Bottomley MJ, Lo Surdo P, Driscoll PC. Bottomley MJ, et al. Curr Biol. 1999 Apr 22;9(8):R301-4. doi: 10.1016/s0960-9822(99)80184-5. Curr Biol. 1999. PMID: 10226017 Free article. Review.
Structural and biochemical characterization of the wild type PCSK9-EGF(AB) complex and natural familial hypercholesterolemia mutants.
Bottomley MJ, Cirillo A, Orsatti L, Ruggeri L, Fisher TS, Santoro JC, Cummings RT, Cubbon RM, Lo Surdo P, Calzetta A, Noto A, Baysarowich J, Mattu M, Talamo F, De Francesco R, Sparrow CP, Sitlani A, Carfí A. Bottomley MJ, et al. J Biol Chem. 2009 Jan 9;284(2):1313-23. doi: 10.1074/jbc.M808363200. Epub 2008 Nov 10. J Biol Chem. 2009. PMID: 19001363 Free article.
109 results