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The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab.
Shima Y, Kuwahara Y, Murota H, Kitaba S, Kawai M, Hirano T, Arimitsu J, Narazaki M, Hagihara K, Ogata A, Katayama I, Kawase I, Kishimoto T, Tanaka T. Shima Y, et al. Among authors: kawai m. Rheumatology (Oxford). 2010 Dec;49(12):2408-12. doi: 10.1093/rheumatology/keq275. Epub 2010 Sep 5. Rheumatology (Oxford). 2010. PMID: 20819796 Free PMC article.
Effect of enzymatically modified isoquercitrin, a flavonoid, on symptoms of Japanese cedar pollinosis: a randomized double-blind placebo-controlled trial.
Kawai M, Hirano T, Arimitsu J, Higa S, Kuwahara Y, Hagihara K, Shima Y, Narazaki M, Ogata A, Koyanagi M, Kai T, Shimizu R, Moriwaki M, Suzuki Y, Ogino S, Kawase I, Tanaka T. Kawai M, et al. Int Arch Allergy Immunol. 2009;149(4):359-68. doi: 10.1159/000205582. Epub 2009 Mar 17. Int Arch Allergy Immunol. 2009. PMID: 19295240 Clinical Trial.
Quantification of hardness, elasticity and viscosity of the skin of patients with systemic sclerosis using a novel sensing device (Vesmeter): a proposal for a new outcome measurement procedure.
Kuwahara Y, Shima Y, Shirayama D, Kawai M, Hagihara K, Hirano T, Arimitsu J, Ogata A, Tanaka T, Kawase I. Kuwahara Y, et al. Among authors: kawai m. Rheumatology (Oxford). 2008 Jul;47(7):1018-24. doi: 10.1093/rheumatology/ken145. Epub 2008 Apr 25. Rheumatology (Oxford). 2008. PMID: 18440998
Luteolin, a flavonoid, inhibits AP-1 activation by basophils.
Hirano T, Higa S, Arimitsu J, Naka T, Ogata A, Shima Y, Fujimoto M, Yamadori T, Ohkawara T, Kuwabara Y, Kawai M, Matsuda H, Yoshikawa M, Maezaki N, Tanaka T, Kawase I, Tanaka T. Hirano T, et al. Among authors: kawai m. Biochem Biophys Res Commun. 2006 Feb 3;340(1):1-7. doi: 10.1016/j.bbrc.2005.11.157. Epub 2005 Dec 6. Biochem Biophys Res Commun. 2006. PMID: 16343431
IL-18 gene polymorphisms affect IL-18 production capability by monocytes.
Arimitsu J, Hirano T, Higa S, Kawai M, Naka T, Ogata A, Shima Y, Fujimoto M, Yamadori T, Hagiwara K, Ohgawara T, Kuwabara Y, Kawase I, Tanaka T. Arimitsu J, et al. Among authors: kawai m. Biochem Biophys Res Commun. 2006 Apr 21;342(4):1413-6. doi: 10.1016/j.bbrc.2006.02.096. Epub 2006 Feb 28. Biochem Biophys Res Commun. 2006. PMID: 16516851 Clinical Trial.
Luteolin, a flavonoid, inhibits CD40 ligand expression by activated human basophils.
Hirano T, Arimitsu J, Higa S, Naka T, Ogata A, Shima Y, Fujimoto M, Yamadori T, Ohkawara T, Kuwabara Y, Kawai M, Kawase I, Tanaka T. Hirano T, et al. Among authors: kawai m. Int Arch Allergy Immunol. 2006;140(2):150-6. doi: 10.1159/000092554. Epub 2006 Apr 4. Int Arch Allergy Immunol. 2006. PMID: 16601352
Flavonoids and related compounds as anti-allergic substances.
Kawai M, Hirano T, Higa S, Arimitsu J, Maruta M, Kuwahara Y, Ohkawara T, Hagihara K, Yamadori T, Shima Y, Ogata A, Kawase I, Tanaka T. Kawai M, et al. Allergol Int. 2007 Jun;56(2):113-23. doi: 10.2332/allergolint.R-06-135. Epub 2007 Mar 1. Allergol Int. 2007. PMID: 17384531 Free article. Review.
Preventative effect of a flavonoid, enzymatically modified isoquercitrin on ocular symptoms of Japanese cedar pollinosis.
Hirano T, Kawai M, Arimitsu J, Ogawa M, Kuwahara Y, Hagihara K, Shima Y, Narazaki M, Ogata A, Koyanagi M, Kai T, Shimizu R, Moriwaki M, Suzuki Y, Ogino S, Kawase I, Tanaka T. Hirano T, et al. Among authors: kawai m. Allergol Int. 2009 Sep;58(3):373-82. doi: 10.2332/allergolint.08-OA-0070. Epub 2009 May 25. Allergol Int. 2009. PMID: 19454839 Free article. Clinical Trial.
2,415 results