McDonald LA - Search Results

1

Discovery of lactoquinomycin and related pyranonaphthoquinones as potent and allosteric inhibitors of AKT/PKB: mechanistic involvement of AKT catalytic activation loop cysteines.

Toral-Barza L, Zhang WG, Huang X, McDonald LA, Salaski EJ, Barbieri LR, Ding WD, Krishnamurthy G, Hu YB, Lucas J, Bernan VS, Cai P, Levin JI, Mansour TS, Gibbons JJ, Abraham RT, Yu K. Toral-Barza L, et al. Among authors: mcdonald la. Mol Cancer Ther. 2007 Nov;6(11):3028-38. doi: 10.1158/1535-7163.MCT-07-0211. Epub 2007 Nov 7. Mol Cancer Ther. 2007. PMID: 17989320

2

Pyranonaphthoquinone lactones: a new class of AKT selective kinase inhibitors alkylate a regulatory loop cysteine.

Salaski EJ, Krishnamurthy G, Ding WD, Yu K, Insaf SS, Eid C, Shim J, Levin JI, Tabei K, Toral-Barza L, Zhang WG, McDonald LA, Honores E, Hanna C, Yamashita A, Johnson B, Li Z, Laakso L, Powell D, Mansour TS. Salaski EJ, et al. Among authors: mcdonald la. J Med Chem. 2009 Apr 23;52(8):2181-4. doi: 10.1021/jm900075g. J Med Chem. 2009. PMID: 19309081

3

In support of the original medermycin/lactoquinomycin A structure.

Williamson RT, McDonald LA, Barbieri LR, Carter GT. Williamson RT, et al. Among authors: mcdonald la. Org Lett. 2002 Dec 26;4(26):4659-62. doi: 10.1021/ol027086g. Org Lett. 2002. PMID: 12489954

4

07H239-A, a new cytotoxic eremophilane sesquiterpene from the marine-derived Xylariaceous fungus LL-07H239.

McDonald LA, Barbieri LR, Bernan VS, Janso J, Lassota P, Carter GT. McDonald LA, et al. J Nat Prod. 2004 Sep;67(9):1565-7. doi: 10.1021/np049924g. J Nat Prod. 2004. PMID: 15387660

5

Muraymycins, novel peptidoglycan biosynthesis inhibitors: semisynthesis and SAR of their derivatives.

Lin YI, Li Z, Francisco GD, McDonald LA, Davis RA, Singh G, Yang Y, Mansour TS. Lin YI, et al. Among authors: mcdonald la. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2341-4. doi: 10.1016/s0960-894x(02)00469-9. Bioorg Med Chem Lett. 2002. PMID: 12161129

6

Structures of the muraymycins, novel peptidoglycan biosynthesis inhibitors.

McDonald LA, Barbieri LR, Carter GT, Lenoy E, Lotvin J, Petersen PJ, Siegel MM, Singh G, Williamson RT. McDonald LA, et al. J Am Chem Soc. 2002 Sep 4;124(35):10260-1. doi: 10.1021/ja017748h. J Am Chem Soc. 2002. PMID: 12197711

7

FTMS structure elucidation of natural products: application to muraymycin antibiotics using ESI multi-CHEF SORI-CID FTMS(n), the top-down/bottom-up approach, and HPLC ESI capillary-skimmer CID FTMS.

McDonald LA, Barbieri LR, Carter GT, Kruppa G, Feng X, Lotvin JA, Siegel MM. McDonald LA, et al. Anal Chem. 2003 Jun 1;75(11):2730-9. doi: 10.1021/ac0264731. Anal Chem. 2003. PMID: 12948143

8

Stereoselective synthesis of an active metabolite of the potent PI3 kinase inhibitor PKI-179.

Chen Z, Venkatesan AM, Dos Santos O, Delos Santos E, Dehnhardt CM, Ayral-Kaloustian S, Ashcroft J, McDonald LA, Mansour TS. Chen Z, et al. Among authors: mcdonald la. J Org Chem. 2010 Mar 5;75(5):1643-51. doi: 10.1021/jo9026269. J Org Chem. 2010. PMID: 20112997

9

The lecanindoles, nonsteroidal progestins from the terrestrial fungus Verticillium lecanii 6144.

Roll DM, Barbieri LR, Bigelis R, McDonald LA, Arias DA, Chang LP, Singh MP, Luckman SW, Berrodin TJ, Yudt MR. Roll DM, et al. Among authors: mcdonald la. J Nat Prod. 2009 Nov;72(11):1944-8. doi: 10.1021/np9004882. J Nat Prod. 2009. PMID: 19863083

10

Fermentative production of self-toxic fungal secondary metabolites.

Singh MP, Leighton MM, Barbieri LR, Roll DM, Urbance SE, Hoshan L, McDonald LA. Singh MP, et al. Among authors: mcdonald la. J Ind Microbiol Biotechnol. 2010 Apr;37(4):335-40. doi: 10.1007/s10295-009-0678-9. Epub 2009 Dec 24. J Ind Microbiol Biotechnol. 2010. PMID: 20033470

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

55 results

Search Page

Filters