Taylor C - Search Results

1

Effect of a new alpha 2 delta ligand PD-217014 on visceral hypersensitivity induced by 2,4,6-trinitrobenzene sulfonic acid in rats.

Ohashi K, Kawai M, Ninomiya N, Taylor C, Kurebayashi Y. Ohashi K, et al. Among authors: taylor c. Pharmacology. 2008;81(2):144-50. doi: 10.1159/000110737. Epub 2007 Nov 7. Pharmacology. 2008. PMID: 17989503

2

Pregabalin is a potent and selective ligand for α(2)δ-1 and α(2)δ-2 calcium channel subunits.

Li Z, Taylor CP, Weber M, Piechan J, Prior F, Bian F, Cui M, Hoffman D, Donevan S. Li Z, et al. Eur J Pharmacol. 2011 Sep 30;667(1-3):80-90. doi: 10.1016/j.ejphar.2011.05.054. Epub 2011 Jun 1. Eur J Pharmacol. 2011. PMID: 21651903

3

Pregabalin action at a model synapse: binding to presynaptic calcium channel alpha2-delta subunit reduces neurotransmission in mice.

Joshi I, Taylor CP. Joshi I, et al. Eur J Pharmacol. 2006 Dec 28;553(1-3):82-8. doi: 10.1016/j.ejphar.2006.09.019. Epub 2006 Sep 23. Eur J Pharmacol. 2006. PMID: 17064682

4

Structure-activity relationships of pregabalin and analogues that target the alpha(2)-delta protein.

Belliotti TR, Capiris T, Ekhato IV, Kinsora JJ, Field MJ, Heffner TG, Meltzer LT, Schwarz JB, Taylor CP, Thorpe AJ, Vartanian MG, Wise LD, Zhi-Su T, Weber ML, Wustrow DJ. Belliotti TR, et al. J Med Chem. 2005 Apr 7;48(7):2294-307. doi: 10.1021/jm049762l. J Med Chem. 2005. PMID: 15801823

5

Anxiolytic-like activity of pregabalin in the Vogel conflict test in α2δ-1 (R217A) and α2δ-2 (R279A) mouse mutants.

Lotarski SM, Donevan S, El-Kattan A, Osgood S, Poe J, Taylor CP, Offord J. Lotarski SM, et al. J Pharmacol Exp Ther. 2011 Aug;338(2):615-21. doi: 10.1124/jpet.111.180976. Epub 2011 May 10. J Pharmacol Exp Ther. 2011. PMID: 21558437

6

Novel cyclopropyl beta-amino acid analogues of pregabalin and gabapentin that target the alpha2-delta protein.

Schwarz JB, Gibbons SE, Graham SR, Colbry NL, Guzzo PR, Le VD, Vartanian MG, Kinsora JJ, Lotarski SM, Li Z, Dickerson MR, Su TZ, Weber ML, El-Kattan A, Thorpe AJ, Donevan SD, Taylor CP, Wustrow DJ. Schwarz JB, et al. J Med Chem. 2005 Apr 21;48(8):3026-35. doi: 10.1021/jm0491086. J Med Chem. 2005. PMID: 15828841

7

Pharmacology and mechanism of action of pregabalin: the calcium channel alpha2-delta (alpha2-delta) subunit as a target for antiepileptic drug discovery.

Taylor CP, Angelotti T, Fauman E. Taylor CP, et al. Epilepsy Res. 2007 Feb;73(2):137-50. doi: 10.1016/j.eplepsyres.2006.09.008. Epub 2006 Nov 28. Epilepsy Res. 2007. PMID: 17126531 Review.

8

Activity profile of pregabalin in rodent models of epilepsy and ataxia.

Vartanian MG, Radulovic LL, Kinsora JJ, Serpa KA, Vergnes M, Bertram E, Taylor CP. Vartanian MG, et al. Epilepsy Res. 2006 Mar;68(3):189-205. doi: 10.1016/j.eplepsyres.2005.11.001. Epub 2005 Dec 5. Epilepsy Res. 2006. PMID: 16337109

9

Brain microdialysis and PK/PD correlation of pregabalin in rats.

Feng MR, Turluck D, Burleigh J, Lister R, Fan C, Middlebrook A, Taylor C, Su T. Feng MR, et al. Among authors: taylor c. Eur J Drug Metab Pharmacokinet. 2001 Jan-Jun;26(1-2):123-8. doi: 10.1007/BF03190385. Eur J Drug Metab Pharmacokinet. 2001. PMID: 11554426

10

Calcium channel alpha2-delta type 1 subunit is the major binding protein for pregabalin in neocortex, hippocampus, amygdala, and spinal cord: an ex vivo autoradiographic study in alpha2-delta type 1 genetically modified mice.

Bian F, Li Z, Offord J, Davis MD, McCormick J, Taylor CP, Walker LC. Bian F, et al. Among authors: taylor cp. Brain Res. 2006 Feb 23;1075(1):68-80. doi: 10.1016/j.brainres.2005.12.084. Epub 2006 Feb 3. Brain Res. 2006. PMID: 16460711

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