Blumenschein W - Search Results

1

TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology.

McGeachy MJ, Bak-Jensen KS, Chen Y, Tato CM, Blumenschein W, McClanahan T, Cua DJ. McGeachy MJ, et al. Among authors: blumenschein w. Nat Immunol. 2007 Dec;8(12):1390-7. doi: 10.1038/ni1539. Epub 2007 Nov 11. Nat Immunol. 2007. PMID: 17994024

2

IL-25 regulates Th17 function in autoimmune inflammation.

Kleinschek MA, Owyang AM, Joyce-Shaikh B, Langrish CL, Chen Y, Gorman DM, Blumenschein WM, McClanahan T, Brombacher F, Hurst SD, Kastelein RA, Cua DJ. Kleinschek MA, et al. J Exp Med. 2007 Jan 22;204(1):161-70. doi: 10.1084/jem.20061738. Epub 2007 Jan 2. J Exp Med. 2007. PMID: 17200411 Free PMC article.

3

Development, cytokine profile and function of human interleukin 17-producing helper T cells.

Wilson NJ, Boniface K, Chan JR, McKenzie BS, Blumenschein WM, Mattson JD, Basham B, Smith K, Chen T, Morel F, Lecron JC, Kastelein RA, Cua DJ, McClanahan TK, Bowman EP, de Waal Malefyt R. Wilson NJ, et al. Nat Immunol. 2007 Sep;8(9):950-7. doi: 10.1038/ni1497. Epub 2007 Aug 5. Nat Immunol. 2007. PMID: 17676044

4

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo.

McGeachy MJ, Chen Y, Tato CM, Laurence A, Joyce-Shaikh B, Blumenschein WM, McClanahan TK, O'Shea JJ, Cua DJ. McGeachy MJ, et al. Nat Immunol. 2009 Mar;10(3):314-24. doi: 10.1038/ni.1698. Epub 2009 Feb 1. Nat Immunol. 2009. PMID: 19182808 Free PMC article.

5

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling.

Boniface K, Bak-Jensen KS, Li Y, Blumenschein WM, McGeachy MJ, McClanahan TK, McKenzie BS, Kastelein RA, Cua DJ, de Waal Malefyt R. Boniface K, et al. J Exp Med. 2009 Mar 16;206(3):535-48. doi: 10.1084/jem.20082293. Epub 2009 Mar 9. J Exp Med. 2009. PMID: 19273625 Free PMC article.

6

Human Th17 cells comprise heterogeneous subsets including IFN-gamma-producing cells with distinct properties from the Th1 lineage.

Boniface K, Blumenschein WM, Brovont-Porth K, McGeachy MJ, Basham B, Desai B, Pierce R, McClanahan TK, Sadekova S, de Waal Malefyt R. Boniface K, et al. J Immunol. 2010 Jul 1;185(1):679-87. doi: 10.4049/jimmunol.1000366. Epub 2010 May 28. J Immunol. 2010. PMID: 20511558

7

Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2.

Chen Y, Haines CJ, Gutcher I, Hochweller K, Blumenschein WM, McClanahan T, Hämmerling G, Li MO, Cua DJ, McGeachy MJ. Chen Y, et al. Immunity. 2011 Mar 25;34(3):409-21. doi: 10.1016/j.immuni.2011.02.011. Immunity. 2011. PMID: 21435588 Free article.

8

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation.

Murphy CA, Langrish CL, Chen Y, Blumenschein W, McClanahan T, Kastelein RA, Sedgwick JD, Cua DJ. Murphy CA, et al. Among authors: blumenschein w. J Exp Med. 2003 Dec 15;198(12):1951-7. doi: 10.1084/jem.20030896. Epub 2003 Dec 8. J Exp Med. 2003. PMID: 14662908 Free PMC article.

9

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6.

Yen D, Cheung J, Scheerens H, Poulet F, McClanahan T, McKenzie B, Kleinschek MA, Owyang A, Mattson J, Blumenschein W, Murphy E, Sathe M, Cua DJ, Kastelein RA, Rennick D. Yen D, et al. Among authors: blumenschein w. J Clin Invest. 2006 May;116(5):1310-6. doi: 10.1172/JCI21404. J Clin Invest. 2006. PMID: 16670770 Free PMC article.

10

Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis.

Chen Y, Langrish CL, McKenzie B, Joyce-Shaikh B, Stumhofer JS, McClanahan T, Blumenschein W, Churakovsa T, Low J, Presta L, Hunter CA, Kastelein RA, Cua DJ. Chen Y, et al. Among authors: blumenschein w. J Clin Invest. 2006 May;116(5):1317-26. doi: 10.1172/JCI25308. J Clin Invest. 2006. PMID: 16670771 Free PMC article.

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