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A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses.
Takahashi K, Shibata T, Akashi-Takamura S, Kiyokawa T, Wakabayashi Y, Tanimura N, Kobayashi T, Matsumoto F, Fukui R, Kouro T, Nagai Y, Takatsu K, Saitoh S, Miyake K. Takahashi K, et al. Among authors: kobayashi t. J Exp Med. 2007 Nov 26;204(12):2963-76. doi: 10.1084/jem.20071132. Epub 2007 Nov 6. J Exp Med. 2007. PMID: 17998391 Free PMC article.
Cathepsins are required for Toll-like receptor 9 responses.
Matsumoto F, Saitoh S, Fukui R, Kobayashi T, Tanimura N, Konno K, Kusumoto Y, Akashi-Takamura S, Miyake K. Matsumoto F, et al. Among authors: kobayashi t. Biochem Biophys Res Commun. 2008 Mar 14;367(3):693-9. doi: 10.1016/j.bbrc.2007.12.130. Epub 2007 Dec 31. Biochem Biophys Res Commun. 2008. PMID: 18166152
Inflammatory responses increase secretion of MD-1 protein.
Thomas Jennings R, Odkhuu E, Nakashima A, Morita N, Kobayashi T, Yamai I, Tanaka M, Suganami T, Haga S, Ozaki M, Watanabe Y, Nagai Y, Takatsu K, Kikuchi-Ueda T, Ichimonji I, Ogawa Y, Takagi H, Yamazaki T, Miyake K, Akashi-Takamura S. Thomas Jennings R, et al. Among authors: kobayashi t. Int Immunol. 2016 Oct;28(10):503-512. doi: 10.1093/intimm/dxw031. Epub 2016 Jun 28. Int Immunol. 2016. PMID: 27352793
C4b binding protein negatively regulates TLR1/2 response.
Morita N, Yamai I, Takahashi K, Kusumoto Y, Shibata T, Kobayashi T, Nonaka MI, Ichimonji I, Takagi H, Miyake K, Takamura SA. Morita N, et al. Among authors: kobayashi t. Innate Immun. 2017 Jan;23(1):11-19. doi: 10.1177/1753425916672312. Epub 2016 Oct 28. Innate Immun. 2017. PMID: 27794068 Free article.
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