Nagle DG - Search Results

1

Total synthesis and absolute configuration of laurenditerpenol: a hypoxia inducible factor-1 activation inhibitor.

Chittiboyina AG, Kumar GM, Carvalho PB, Liu Y, Zhou YD, Nagle DG, Avery MA. Chittiboyina AG, et al. Among authors: nagle dg. J Med Chem. 2007 Dec 13;50(25):6299-302. doi: 10.1021/jm7011062. Epub 2007 Nov 16. J Med Chem. 2007. PMID: 18004798 Free PMC article.

2

A new indanone from the marine cyanobacterium Lyngbya majuscula that inhibits hypoxia-induced activation of the VEGF promoter in Hep3B cells.

Nagle DG, Zhou YD, Park PU, Paul VJ, Rajbhandari I, Duncan CJ, Pasco DS. Nagle DG, et al. J Nat Prod. 2000 Oct;63(10):1431-3. doi: 10.1021/np000216e. J Nat Prod. 2000. PMID: 11076571

3

Molecular-targeted antitumor agents: the Saururus cernuus dineolignans manassantin B and 4-O-demethylmanassantin B are potent inhibitors of hypoxia-activated HIF-1.

Hodges TW, Hossain CF, Kim YP, Zhou YD, Nagle DG. Hodges TW, et al. Among authors: nagle dg. J Nat Prod. 2004 May;67(5):767-71. doi: 10.1021/np030514m. J Nat Prod. 2004. PMID: 15165135

4

Mechanism targeted discovery of antitumor marine natural products.

Nagle DG, Zhou YD, Mora FD, Mohammed KA, Kim YP. Nagle DG, et al. Curr Med Chem. 2004 Jul;11(13):1725-56. doi: 10.2174/0929867043364991. Curr Med Chem. 2004. PMID: 15279579 Free PMC article. Review.

5

Laurenditerpenol, a new diterpene from the tropical marine alga Laurenciaintricata that potently inhibits HIF-1 mediated hypoxic signaling in breast tumor cells.

Mohammed KA, Hossain CF, Zhang L, Bruick RK, Zhou YD, Nagle DG. Mohammed KA, et al. Among authors: nagle dg. J Nat Prod. 2004 Dec;67(12):2002-7. doi: 10.1021/np049753f. J Nat Prod. 2004. PMID: 15620241 Free PMC article.

6

Hypoxia-inducible factor-1 activation by (-)-epicatechin gallate: potential adverse effects of cancer chemoprevention with high-dose green tea extracts.

Zhou YD, Kim YP, Li XC, Baerson SR, Agarwal AK, Hodges TW, Ferreira D, Nagle DG. Zhou YD, et al. Among authors: nagle dg. J Nat Prod. 2004 Dec;67(12):2063-9. doi: 10.1021/np040140c. J Nat Prod. 2004. PMID: 15620252 Free PMC article.

7

Saururus cernuus lignans--potent small molecule inhibitors of hypoxia-inducible factor-1.

Hossain CF, Kim YP, Baerson SR, Zhang L, Bruick RK, Mohammed KA, Agarwal AK, Nagle DG, Zhou YD. Hossain CF, et al. Among authors: nagle dg. Biochem Biophys Res Commun. 2005 Aug 5;333(3):1026-33. doi: 10.1016/j.bbrc.2005.05.191. Biochem Biophys Res Commun. 2005. PMID: 15967416 Free PMC article.

8

Terpenoid tetrahydroisoquinoline alkaloids emetine, klugine, and isocephaeline inhibit the activation of hypoxia-inducible factor-1 in breast tumor cells.

Zhou YD, Kim YP, Mohammed KA, Jones DK, Muhammad I, Dunbar DC, Nagle DG. Zhou YD, et al. Among authors: nagle dg. J Nat Prod. 2005 Jun;68(6):947-50. doi: 10.1021/np050029m. J Nat Prod. 2005. PMID: 15974627 Free PMC article.

9

Natural product-based inhibitors of hypoxia-inducible factor-1 (HIF-1).

Nagle DG, Zhou YD. Nagle DG, et al. Curr Drug Targets. 2006 Mar;7(3):355-69. doi: 10.2174/138945006776054979. Curr Drug Targets. 2006. PMID: 16515532 Free PMC article. Review.

10

Bioassay for the identification of natural product-based activators of peroxisome proliferator-activated receptor-gamma (PPARgamma): the marine sponge metabolite psammaplin A activates PPARgamma and induces apoptosis in human breast tumor cells.

Mora FD, Jones DK, Desai PV, Patny A, Avery MA, Feller DR, Smillie T, Zhou YD, Nagle DG. Mora FD, et al. Among authors: nagle dg. J Nat Prod. 2006 Apr;69(4):547-52. doi: 10.1021/np050397q. J Nat Prod. 2006. PMID: 16643023

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