Dahl R - Search Results

1

Preclinical studies of celastrol and acetyl isogambogic acid in melanoma.

Abbas S, Bhoumik A, Dahl R, Vasile S, Krajewski S, Cosford ND, Ronai ZA. Abbas S, et al. Among authors: dahl r. Clin Cancer Res. 2007 Nov 15;13(22 Pt 1):6769-78. doi: 10.1158/1078-0432.CCR-07-1536. Clin Cancer Res. 2007. PMID: 18006779 Free PMC article.

2

Rapid multistep synthesis of 1,2,4-oxadiazoles in a single continuous microreactor sequence.

Grant D, Dahl R, Cosford ND. Grant D, et al. Among authors: dahl r. J Org Chem. 2008 Sep 19;73(18):7219-23. doi: 10.1021/jo801152c. Epub 2008 Aug 8. J Org Chem. 2008. PMID: 18687005 Free PMC article.

3

Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors.

Noberini R, Koolpe M, Peddibhotla S, Dahl R, Su Y, Cosford ND, Roth GP, Pasquale EB. Noberini R, et al. Among authors: dahl r. J Biol Chem. 2008 Oct 24;283(43):29461-72. doi: 10.1074/jbc.M804103200. Epub 2008 Aug 26. J Biol Chem. 2008. PMID: 18728010 Free PMC article.

4

Fully automated continuous flow synthesis of highly functionalized imidazo[1,2-a] heterocycles.

Herath A, Dahl R, Cosford ND. Herath A, et al. Among authors: dahl r. Org Lett. 2010 Feb 5;12(3):412-5. doi: 10.1021/ol902433a. Org Lett. 2010. PMID: 20038130 Free PMC article.

5

Inhibition of hematopoietic protein tyrosine phosphatase augments and prolongs ERK1/2 and p38 activation.

Sergienko E, Xu J, Liu WH, Dahl R, Critton DA, Su Y, Brown BT, Chan X, Yang L, Bobkova EV, Vasile S, Yuan H, Rascon J, Colayco S, Sidique S, Cosford ND, Chung TD, Mustelin T, Page R, Lombroso PJ, Tautz L. Sergienko E, et al. Among authors: dahl r. ACS Chem Biol. 2012 Feb 17;7(2):367-77. doi: 10.1021/cb2004274. Epub 2011 Nov 17. ACS Chem Biol. 2012. PMID: 22070201 Free PMC article.

6

Pharmacological inhibition of PHOSPHO1 suppresses vascular smooth muscle cell calcification.

Kiffer-Moreira T, Yadav MC, Zhu D, Narisawa S, Sheen C, Stec B, Cosford ND, Dahl R, Farquharson C, Hoylaerts MF, Macrae VE, Millán JL. Kiffer-Moreira T, et al. Among authors: dahl r. J Bone Miner Res. 2013 Jan;28(1):81-91. doi: 10.1002/jbmr.1733. J Bone Miner Res. 2013. PMID: 22887744 Free PMC article.

7

Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1.

Bravo Y, Teriete P, Dhanya RP, Dahl R, Lee PS, Kiffer-Moreira T, Ganji SR, Sergienko E, Smith LH, Farquharson C, Millán JL, Cosford ND. Bravo Y, et al. Among authors: dahl r. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4308-11. doi: 10.1016/j.bmcl.2014.07.013. Epub 2014 Jul 15. Bioorg Med Chem Lett. 2014. PMID: 25124115 Free PMC article.

8

Chemical biology strategy reveals pathway-selective inhibitor of NF-kappaB activation induced by protein kinase C.

Shi R, Re D, Dudl E, Cuddy M, Okolotowicz KJ, Dahl R, Su Y, Hurder A, Kitada S, Peddibhotla S, Roth GP, Smith LH, Kipps TJ, Cosford N, Cashman J, Reed JC. Shi R, et al. Among authors: dahl r. ACS Chem Biol. 2010 Mar 19;5(3):287-99. doi: 10.1021/cb9003089. ACS Chem Biol. 2010. PMID: 20141195 Free PMC article.

9

Discovery and validation of a series of aryl sulfonamides as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP).

Dahl R, Sergienko EA, Su Y, Mostofi YS, Yang L, Simao AM, Narisawa S, Brown B, Mangravita-Novo A, Vicchiarelli M, Smith LH, O'Neill WC, Millán JL, Cosford ND. Dahl R, et al. J Med Chem. 2009 Nov 12;52(21):6919-25. doi: 10.1021/jm900383s. J Med Chem. 2009. PMID: 19821572 Free PMC article.

10

The mGluR2 positive allosteric modulator BINA decreases cocaine self-administration and cue-induced cocaine-seeking and counteracts cocaine-induced enhancement of brain reward function in rats.

Jin X, Semenova S, Yang L, Ardecky R, Sheffler DJ, Dahl R, Conn PJ, Cosford ND, Markou A. Jin X, et al. Among authors: dahl r. Neuropsychopharmacology. 2010 Sep;35(10):2021-36. doi: 10.1038/npp.2010.82. Epub 2010 Jun 16. Neuropsychopharmacology. 2010. PMID: 20555310 Free PMC article.

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