Grosveld GC - Search Results

1

Overexpression of N-Myc rapidly causes acute myeloid leukemia in mice.

Kawagoe H, Kandilci A, Kranenburg TA, Grosveld GC. Kawagoe H, et al. Among authors: grosveld gc. Cancer Res. 2007 Nov 15;67(22):10677-85. doi: 10.1158/0008-5472.CAN-07-1118. Cancer Res. 2007. PMID: 18006809

2

TEL2, an ETS factor expressed in human leukemia, regulates monocytic differentiation of U937 Cells and blocks the inhibitory effect of TEL1 on ras-induced cellular transformation.

Kawagoe H, Potter M, Ellis J, Grosveld GC. Kawagoe H, et al. Among authors: grosveld gc. Cancer Res. 2004 Sep 1;64(17):6091-100. doi: 10.1158/0008-5472.CAN-04-0839. Cancer Res. 2004. PMID: 15342392

3

MN1-TEL myeloid oncoprotein expressed in multipotent progenitors perturbs both myeloid and lymphoid growth and causes T-lymphoid tumors in mice.

Kawagoe H, Grosveld GC. Kawagoe H, et al. Among authors: grosveld gc. Blood. 2005 Dec 15;106(13):4278-86. doi: 10.1182/blood-2005-04-1674. Epub 2005 Aug 4. Blood. 2005. PMID: 16081688 Free PMC article.

4

Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9.

Kawagoe H, Grosveld GC. Kawagoe H, et al. Among authors: grosveld gc. Blood. 2005 Dec 15;106(13):4269-77. doi: 10.1182/blood-2005-04-1679. Epub 2005 Aug 16. Blood. 2005. PMID: 16105979 Free PMC article.

5

MN1 overexpression is an important step in the development of inv(16) AML.

Carella C, Bonten J, Sirma S, Kranenburg TA, Terranova S, Klein-Geltink R, Shurtleff S, Downing JR, Zwarthoff EC, Liu PP, Grosveld GC. Carella C, et al. Among authors: grosveld gc. Leukemia. 2007 Aug;21(8):1679-90. doi: 10.1038/sj.leu.2404778. Epub 2007 May 24. Leukemia. 2007. PMID: 17525718

6

High MN1 expression increases the in vitro clonogenic activity of primary mouse B-cells.

Numata M, Yener MD, Ekmekçi SS, Aydın M, Grosveld G, Cardone M, Terranova S, Geltink RK, Özbek U, Özçelik E, Güleç Ç, Anak S, Karaman S, Öztürk G, Akbıyık M, Kandilci A. Numata M, et al. Leuk Res. 2015 Aug;39(8):906-12. doi: 10.1016/j.leukres.2015.05.013. Epub 2015 Jun 12. Leuk Res. 2015. PMID: 26111797 Free PMC article.

7

The novel ETS factor TEL2 cooperates with Myc in B lymphomagenesis.

Cardone M, Kandilci A, Carella C, Nilsson JA, Brennan JA, Sirma S, Ozbek U, Boyd K, Cleveland JL, Grosveld GC. Cardone M, et al. Among authors: grosveld gc. Mol Cell Biol. 2005 Mar;25(6):2395-405. doi: 10.1128/MCB.25.6.2395-2405.2005. Mol Cell Biol. 2005. PMID: 15743832 Free PMC article.

8

SET-CAN, the product of the t(9;9) in acute undifferentiated leukemia, causes expansion of early hematopoietic progenitors and hyperproliferation of stomach mucosa in transgenic mice.

Ozbek U, Kandilci A, van Baal S, Bonten J, Boyd K, Franken P, Fodde R, Grosveld GC. Ozbek U, et al. Among authors: grosveld gc. Am J Pathol. 2007 Aug;171(2):654-66. doi: 10.2353/ajpath.2007.060934. Epub 2007 Jun 14. Am J Pathol. 2007. PMID: 17569777 Free PMC article.

9

Reintroduction of CEBPA in MN1-overexpressing hematopoietic cells prevents their hyperproliferation and restores myeloid differentiation.

Kandilci A, Grosveld GC. Kandilci A, et al. Among authors: grosveld gc. Blood. 2009 Aug 20;114(8):1596-606. doi: 10.1182/blood-2009-02-205443. Epub 2009 Jun 26. Blood. 2009. PMID: 19561324 Free PMC article.

10

Mapping of MN1 sequences necessary for myeloid transformation.

Kandilci A, Surtel J, Janke L, Neale G, Terranova S, Grosveld GC. Kandilci A, et al. Among authors: grosveld gc. PLoS One. 2013 Apr 23;8(4):e61706. doi: 10.1371/journal.pone.0061706. Print 2013. PLoS One. 2013. PMID: 23626719 Free PMC article.

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