Lykkegaard K - Search Results

1

Upregulation of the brainstem preproglucagon system in the obese Zucker rat.

Vrang N, Larsen PJ, Jensen PB, Lykkegaard K, Artmann A, Larsen LK, Tang-Christensen M. Vrang N, et al. Among authors: lykkegaard k. Brain Res. 2008 Jan 2;1187:116-24. doi: 10.1016/j.brainres.2007.10.026. Epub 2007 Oct 22. Brain Res. 2008. PMID: 18022140

2

Long-term characterization of the diet-induced obese and diet-resistant rat model: a polygenetic rat model mimicking the human obesity syndrome.

Madsen AN, Hansen G, Paulsen SJ, Lykkegaard K, Tang-Christensen M, Hansen HS, Levin BE, Larsen PJ, Knudsen LB, Fosgerau K, Vrang N. Madsen AN, et al. Among authors: lykkegaard k. J Endocrinol. 2010 Sep;206(3):287-96. doi: 10.1677/JOE-10-0004. Epub 2010 May 27. J Endocrinol. 2010. PMID: 20508079

3

Combination of the insulin sensitizer, pioglitazone, and the long-acting GLP-1 human analog, liraglutide, exerts potent synergistic glucose-lowering efficacy in severely diabetic ZDF rats.

Larsen PJ, Wulff EM, Gotfredsen CF, Brand CL, Sturis J, Vrang N, Knudsen LB, Lykkegaard K. Larsen PJ, et al. Among authors: lykkegaard k. Diabetes Obes Metab. 2008 Apr;10(4):301-11. doi: 10.1111/j.1463-1326.2008.00865.x. Diabetes Obes Metab. 2008. PMID: 18333889

4

The once-daily human GLP-1 analog, liraglutide, reduces olanzapine-induced weight gain and glucose intolerance.

Lykkegaard K, Larsen PJ, Vrang N, Bock C, Bock T, Knudsen LB. Lykkegaard K, et al. Schizophr Res. 2008 Aug;103(1-3):94-103. doi: 10.1016/j.schres.2008.05.011. Epub 2008 Jun 25. Schizophr Res. 2008. PMID: 18579346

5

Characterization of beta-cell mass and insulin resistance in diet-induced obese and diet-resistant rats.

Paulsen SJ, Jelsing J, Madsen AN, Hansen G, Lykkegaard K, Larsen LK, Larsen PJ, Levin BE, Vrang N. Paulsen SJ, et al. Among authors: lykkegaard k. Obesity (Silver Spring). 2010 Feb;18(2):266-73. doi: 10.1038/oby.2009.245. Epub 2009 Aug 6. Obesity (Silver Spring). 2010. PMID: 19661956 Free article.

6

Dissociation of antihyperglycaemic and adverse effects of partial perioxisome proliferator-activated receptor (PPAR-gamma) agonist balaglitazone.

Larsen PJ, Lykkegaard K, Larsen LK, Fleckner J, Sauerberg P, Wassermann K, Wulff EM. Larsen PJ, et al. Among authors: lykkegaard k. Eur J Pharmacol. 2008 Oct 31;596(1-3):173-9. doi: 10.1016/j.ejphar.2008.08.004. Epub 2008 Aug 16. Eur J Pharmacol. 2008. PMID: 18761337

7

Myocardial Changes in Diabetic and Nondiabetic Nonhuman Primates.

Krog S, Ludvigsen TP, Nielsen OL, Kirk RK, Lykkegaard K, Wulff EM, Møller JE, Pedersen HD, Olsen LH. Krog S, et al. Among authors: lykkegaard k. Vet Pathol. 2020 Mar;57(2):332-343. doi: 10.1177/0300985820901332. Epub 2020 Feb 25. Vet Pathol. 2020. PMID: 32096447

8

FGF21 decreases food intake and body weight in obese Göttingen minipigs.

Christoffersen B, Straarup EM, Lykkegaard K, Fels JJ, Sass-Ørum K, Zhang X, Raun K, Andersen B. Christoffersen B, et al. Among authors: lykkegaard k. Diabetes Obes Metab. 2019 Mar;21(3):592-600. doi: 10.1111/dom.13560. Epub 2018 Nov 20. Diabetes Obes Metab. 2019. PMID: 30328263

9

Differential receptor selectivity of the FGF15/FGF19 orthologues determines distinct metabolic activities in db/db mice.

Hansen AMK, Vienberg SG, Lykkegaard K, Zhao X, Tingqing G, Han D, Zhang X, Thøgersen H, Sass-Ørum K, Tagmose T, Raun K, Andersen B. Hansen AMK, et al. Among authors: lykkegaard k. Biochem J. 2018 Sep 25;475(18):2985-2996. doi: 10.1042/BCJ20180555. Biochem J. 2018. PMID: 30127091

10

Development of Zalfermin, a Long-Acting Proteolytically Stabilized FGF21 Analog.

Sass-Ørum K, Tagmose TM, Olsen J, Sjölander A, Wahlund PO, Han D, Vegge A, Reedtz-Runge S, Wang Z, Gao X, Wieczorek B, Lamberth K, Lykkegaard K, Nielsen PK, Thøgersen H, Yu M, Wang J, Drustrup J, Zhang X, Garibay P, Hansen K, Hansen AMK, Andersen B. Sass-Ørum K, et al. Among authors: lykkegaard k. J Med Chem. 2024 Jul 25;67(14):11769-11788. doi: 10.1021/acs.jmedchem.4c00391. Epub 2024 Jul 16. J Med Chem. 2024. PMID: 39013015 Free PMC article.

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