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Page 1
The α2δ Subunit and Absence Epilepsy: Beyond Calcium Channels?
Celli R, Santolini I, Guiducci M, van Luijtelaar G, Parisi P, Striano P, Gradini R, Battaglia G, Ngomba RT, Nicoletti F. Celli R, et al. Among authors: santolini i. Curr Neuropharmacol. 2017;15(6):918-925. doi: 10.2174/1570159X15666170309105451. Curr Neuropharmacol. 2017. PMID: 28290248 Free PMC article. Review.
Pharmacological activation of mGlu5 receptors with the positive allosteric modulator VU0360172, modulates thalamic GABAergic transmission.
Celli R, Wall MJ, Santolini I, Vergassola M, Di Menna L, Mascio G, Cannella M, van Luijtelaar G, Pittaluga A, Ciruela F, Bruno V, Nicoletti F, Ngomba RT. Celli R, et al. Among authors: santolini i. Neuropharmacology. 2020 Nov 1;178:108240. doi: 10.1016/j.neuropharm.2020.108240. Epub 2020 Aug 6. Neuropharmacology. 2020. PMID: 32768418
Protective role for type-1 metabotropic glutamate receptors against spike and wave discharges in the WAG/Rij rat model of absence epilepsy.
Ngomba RT, Santolini I, Biagioni F, Molinaro G, Simonyi A, van Rijn CM, D'Amore V, Mastroiacovo F, Olivieri G, Gradini R, Ferraguti F, Battaglia G, Bruno V, Puliti A, van Luijtelaar G, Nicoletti F. Ngomba RT, et al. Among authors: santolini i. Neuropharmacology. 2011 Jun;60(7-8):1281-91. doi: 10.1016/j.neuropharm.2011.01.007. Epub 2011 Jan 26. Neuropharmacology. 2011. PMID: 21277877
Potentiation of mGlu5 receptors with the novel enhancer, VU0360172, reduces spontaneous absence seizures in WAG/Rij rats.
D'Amore V, Santolini I, van Rijn CM, Biagioni F, Molinaro G, Prete A, Conn PJ, Lindsley CW, Zhou Y, Vinson PN, Rodriguez AL, Jones CK, Stauffer SR, Nicoletti F, van Luijtelaar G, Ngomba RT. D'Amore V, et al. Among authors: santolini i. Neuropharmacology. 2013 Mar;66:330-8. doi: 10.1016/j.neuropharm.2012.05.044. Epub 2012 Jun 15. Neuropharmacology. 2013. PMID: 22705340 Free PMC article.
Head-to head comparison of mGlu1 and mGlu5 receptor activation in chronic treatment of absence epilepsy in WAG/Rij rats.
D'Amore V, Santolini I, Celli R, Lionetto L, De Fusco A, Simmaco M, van Rijn CM, Vieira E, Stauffer SR, Conn PJ, Bosco P, Nicoletti F, van Luijtelaar G, Ngomba RT. D'Amore V, et al. Among authors: santolini i. Neuropharmacology. 2014 Oct;85:91-103. doi: 10.1016/j.neuropharm.2014.05.005. Epub 2014 May 20. Neuropharmacology. 2014. PMID: 24859611 Free PMC article.
Alterations in the α2 δ ligand, thrombospondin-1, in a rat model of spontaneous absence epilepsy and in patients with idiopathic/genetic generalized epilepsies.
Santolini I, Celli R, Cannella M, Imbriglio T, Guiducci M, Parisi P, Schubert J, Iacomino M, Zara F, Lerche H; EuroEPINOMICS CoGIE Consortium; Genetic Commission of Italian League Against Epilepsy (LICE); Moyanova S, Ngomba RT, van Luijtelaar G, Battaglia G, Bruno V, Striano P, Nicoletti F. Santolini I, et al. Epilepsia. 2017 Nov;58(11):1993-2001. doi: 10.1111/epi.13898. Epub 2017 Sep 15. Epilepsia. 2017. PMID: 28913875
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