Dent P - Search Results

1

Melanoma differentiation associated gene-7/interleukin-24 reverses multidrug resistance in human colorectal cancer cells.

Emdad L, Lebedeva IV, Su ZZ, Sarkar D, Dent P, Curiel DT, Fisher PB. Emdad L, et al. Among authors: dent p. Mol Cancer Ther. 2007 Nov;6(11):2985-94. doi: 10.1158/1535-7163.MCT-07-0399. Mol Cancer Ther. 2007. PMID: 18025283

2

mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.

Sarkar D, Su ZZ, Lebedeva IV, Sauane M, Gopalkrishnan RV, Valerie K, Dent P, Fisher PB. Sarkar D, et al. Among authors: dent p. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):10054-9. doi: 10.1073/pnas.152327199. Epub 2002 Jul 11. Proc Natl Acad Sci U S A. 2002. PMID: 12114539 Free PMC article.

3

Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.

Su ZZ, Lebedeva IV, Sarkar D, Gopalkrishnan RV, Sauane M, Sigmon C, Yacoub A, Valerie K, Dent P, Fisher PB. Su ZZ, et al. Among authors: dent p. Oncogene. 2003 Feb 27;22(8):1164-80. doi: 10.1038/sj.onc.1206062. Oncogene. 2003. PMID: 12606943

4

mda-7/IL-24, a novel cancer selective apoptosis inducing cytokine gene: from the laboratory into the clinic.

Fisher PB, Gopalkrishnan RV, Chada S, Ramesh R, Grimm EA, Rosenfeld MR, Curiel DT, Dent P. Fisher PB, et al. Among authors: dent p. Cancer Biol Ther. 2003 Jul-Aug;2(4 Suppl 1):S23-37. Cancer Biol Ther. 2003. PMID: 14508078 Review.

5

Bcl-2 and Bcl-x(L) differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24.

Lebedeva IV, Sarkar D, Su ZZ, Kitada S, Dent P, Stein CA, Reed JC, Fisher PB. Lebedeva IV, et al. Among authors: dent p. Oncogene. 2003 Nov 27;22(54):8758-73. doi: 10.1038/sj.onc.1206891. Oncogene. 2003. PMID: 14647471

6

Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species.

Lebedeva IV, Su ZZ, Sarkar D, Kitada S, Dent P, Waxman S, Reed JC, Fisher PB. Lebedeva IV, et al. Among authors: dent p. Cancer Res. 2003 Dec 1;63(23):8138-44. Cancer Res. 2003. PMID: 14678967

7

Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways.

Sauane M, Lebedeva IV, Su ZZ, Choo HT, Randolph A, Valerie K, Dent P, Gopalkrishnan RV, Fisher PB. Sauane M, et al. Among authors: dent p. Cancer Res. 2004 May 1;64(9):2988-93. doi: 10.1158/0008-5472.can-04-0200. Cancer Res. 2004. PMID: 15126330

8

Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis.

Lebedeva IV, Su ZZ, Sarkar D, Gopalkrishnan RV, Waxman S, Yacoub A, Dent P, Fisher PB. Lebedeva IV, et al. Among authors: dent p. Oncogene. 2005 Jan 20;24(4):585-96. doi: 10.1038/sj.onc.1208183. Oncogene. 2005. PMID: 15580305

9

mda-7/IL-24: exploiting cancer's Achilles' heel.

Lebedeva IV, Sauane M, Gopalkrishnan RV, Sarkar D, Su ZZ, Gupta P, Nemunaitis J, Cunningham C, Yacoub A, Dent P, Fisher PB. Lebedeva IV, et al. Among authors: dent p. Mol Ther. 2005 Jan;11(1):4-18. doi: 10.1016/j.ymthe.2004.08.012. Mol Ther. 2005. PMID: 15585401 Free article. Review.

10

Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells.

Su Z, Emdad L, Sauane M, Lebedeva IV, Sarkar D, Gupta P, James CD, Randolph A, Valerie K, Walter MR, Dent P, Fisher PB. Su Z, et al. Among authors: dent p. Oncogene. 2005 Nov 17;24(51):7552-66. doi: 10.1038/sj.onc.1208911. Oncogene. 2005. PMID: 16044151

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