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Delayed attainment of full donor chimaerism following alemtuzumab-based reduced-intensity conditioning haematopoeitic stem cell transplantation for acute myeloid leukaemia and myelodysplastic syndromes is associated with improved outcomes.
Lim ZY, Pearce L, Ho AY, Barber L, Ingram W, Usai M, Tobal K, Devereux S, Pagliuca A, Mufti GJ. Lim ZY, et al. Among authors: pearce l. Br J Haematol. 2007 Aug;138(4):517-26. doi: 10.1111/j.1365-2141.2007.06676.x. Epub 2007 Jun 29. Br J Haematol. 2007. PMID: 17608767 Free article.
Imbalance of effector and regulatory CD4 T cells is associated with graft-versus-host disease after hematopoietic stem cell transplantation using a reduced intensity conditioning regimen and alemtuzumab.
Matthews K, Lim Z, Afzali B, Pearce L, Abdallah A, Kordasti S, Pagliuca A, Lombardi G, Madrigal JA, Mufti GJ, Barber LD. Matthews K, et al. Among authors: pearce l. Haematologica. 2009 Jul;94(7):956-66. doi: 10.3324/haematol.2008.003103. Epub 2009 Jun 2. Haematologica. 2009. PMID: 19491336 Free PMC article. Clinical Trial.
Rapid recovery of lymphocyte subsets is not associated with protection from relapse of myelodysplastic syndromes and acute myeloid leukaemia after haematopoietic stem cell transplantation using a reduced intensity conditioning regimen and alemtuzumab.
Matthews K, Lim Z, Pearce L, Pagliuca A, Alejandro Madrigal J, Mufti GJ, Barber LD. Matthews K, et al. Among authors: pearce l. Br J Haematol. 2010 Jun;149(6):879-89. doi: 10.1111/j.1365-2141.2010.08164.x. Epub 2010 Mar 21. Br J Haematol. 2010. PMID: 20346011 Free article.
Mimicking the tumour microenvironment: three different co-culture systems induce a similar phenotype but distinct proliferative signals in primary chronic lymphocytic leukaemia cells.
Hamilton E, Pearce L, Morgan L, Robinson S, Ware V, Brennan P, Thomas NS, Yallop D, Devereux S, Fegan C, Buggins AG, Pepper C. Hamilton E, et al. Among authors: pearce l. Br J Haematol. 2012 Sep;158(5):589-99. doi: 10.1111/j.1365-2141.2012.09191.x. Epub 2012 Jun 19. Br J Haematol. 2012. PMID: 22712573 Free article.
Monitoring of chimerism following allogeneic haematopoietic stem cell transplantation (HSCT): technical recommendations for the use of short tandem repeat (STR) based techniques, on behalf of the United Kingdom National External Quality Assessment Service for Leucocyte Immunophenotyping Chimerism Working Group.
Clark JR, Scott SD, Jack AL, Lee H, Mason J, Carter GI, Pearce L, Jackson T, Clouston H, Sproul A, Keen L, Molloy K, Folarin N, Whitby L, Snowden JA, Reilly JT, Barnett D; United Kingdom National External Quality Assessment Service for Leucocyte Immunophenotyping Chimerism Working Group. Clark JR, et al. Among authors: pearce l. Br J Haematol. 2015 Jan;168(1):26-37. doi: 10.1111/bjh.13073. Epub 2014 Aug 22. Br J Haematol. 2015. PMID: 25145701 Free article.
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